Results 151 to 160 of about 31,902 (254)

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

open access: yesAdvanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu   +7 more
wiley   +1 more source

Kaempferol Attenuates Spaceflight‐Associated Knee Cartilage Degradation by Targeting NOX4‐Mediated Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
We have shown that both simulated and actual spaceflight contribute to cartilage degradation in the knees of mice. Using RNA sequencing and bioenergetic profiling, we identified NADPH oxidase 4 (NOX4) as a key factor driving these changes. Additionally, we found that kaempferol, a naturally occurring flavonoid that binds directly to NOX4, reduces ...
Yuesong Yin   +23 more
wiley   +1 more source

A Bio‐Functional Mimetic Robot for Versatile Tasks From Cross‐Scale Manipulation to Limb‐Tool Integration

open access: yesAdvanced Science, EarlyView.
A functionally biomimetic design methodology is presented, enabling a single robot to perform eight distinct functions and manipulate objects across a size range exceeding 2300‐fold. The robot exceeds basic human hand functions and demonstrates remote operation, multi‐object manipulation, humanoid‐robot hand interaction, and narrow‐space inspection ...
Xin Tong   +7 more
wiley   +1 more source

Origami Metamaterials Based on Low‐Melting‐Point Alloy Phase Transition: Breaking the Trade‐Off Between Reusability and Energy Absorption Quality

open access: yesAdvanced Science, EarlyView.
This work presents an origami metamaterial that integrates a low‐melting‐point alloy skeleton into an elastomeric shell. It dissipates energy through the metal's plastic deformation and recovers through the solid–liquid phase transition of the alloy together with the hyperelasticity of the shell.
Yupeng Liu   +5 more
wiley   +1 more source

Strategy of Triple‐Gradient in Binary Pixels for Flexible Pressure Sensing with High Sensitivity and Wide‐Range Linearity

open access: yesAdvanced Science, EarlyView.
A flexible pressure sensor with triple‐gradient design of conductivity, modulus, and dimension in binary micro‐dome pixels is proposed. Based on precisely‐designed CNT/PDMS matrix, the device exhibits a linear sensitivity of 974.1 kPa−1 across range up to 1.8 MPa (R2 > 0.99), offering an effective strategy for potential applications in healthcare ...
Yifan Liu   +9 more
wiley   +1 more source

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