Results 141 to 150 of about 1,161,651 (341)

Engineering a Molecular Missile for Pancreatic Cancer Detection: Vector Design [PDF]

, 2018
Pancreatic cancer, though rare, is expected to be the second-leading cause of cancer-related death by 2030 (Rahib et al., 2014). CA 19-9 is currently the most widely used biomarker for pancreatic cancer detection, but detection of CA 19-9 relies on the ...
Castillo, Sophia, Zhang, Zhiwen
core   +1 more source

Interphase Self‐Optimization Enables Stable Magnesium Anode in Hydrogel Electrolyte

Advanced Materials, EarlyView.
Based on a MgCl2 hydrogel electrolyte, we identify a tridentate chelant additive to construct a magnesium oxychloride interphase on Mg metal anodes. This self‐optimized interphase enables low‐resistance Mg2+ stripping/plating, resulting in much elongated cycling life of 600 h with 0.24 V nucleation overpotential.
Xinyuan Zhang, Hengyue Xu, Heng Jiang, Fei Du, Hong Jin Fan   +4 more
wiley   +1 more source

Unnatural Amino Acid Crosslinking for Increased Spatiotemporal Resolution of Chromatin Dynamics. [PDF]

Int J Mol Sci, 2023
Moleri P, Wilkins BJ.
europepmc   +1 more source

Immune and Stem Cell‐Mediated Bactericidal Amplification and Bone Remodeling for Infection Clearance and Osteointegration

Advanced Materials, EarlyView.
A pH‐responsive biomaterial interface integrates bactericidal peptides, cell‐recruiting peptides, and magnesium ions into a multifunctional system. Infection‐induced acidification triggers antimicrobial peptide release while cell‐recruiting peptides mobilize bone marrow stem cells.
Zhenyu Li, Siming Zhang, Jiale Dong, Ning Li, Mo Chen, Kunzheng Wang, Bin Li, Guoqing Pan, Jiaxiang Bai, Chen Zhu   +9 more
wiley   +1 more source

A robust yeast biocontainment system with two-layered regulation switch dependent on unnatural amino acid. [PDF]

Nat Commun, 2023
Chang T, Ding W, Yan S, Wang Y, Zhang H, Zhang Y, Ping Z, Zhang H, Huang Y, Zhang J, Wang D, Zhang W, Xu X, Shen Y, Fu X.   +14 more
europepmc   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

Advanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li, Tianfang Wang, Nicolas Soro, Guoying Ni, Meg Allom, D. İpek Kurtböke, Xiaosong Liu, Damon Kent   +7 more
wiley   +1 more source

Pyrrolysine-Inspired in Cellulo Synthesis of an Unnatural Amino Acid for Facile Macrocyclization of Proteins. [PDF]

J Am Chem Soc, 2023
Tai J, Wang L, Chan WS, Cheng J, Chan YH, Lee MM, Chan MK.   +6 more
europepmc   +1 more source

Engineering Synthetic Antibody by Expanded Genetic Code [PDF]

, 2017
Antibodies are extensively used in research for diagnostic and therapeutic purposes because of their unrivaled specificity and biomarker binding strengths.1 Currently, monoclonal antibodies are most commonly used because of their production consistency ...
Batiuk, Elizabeth, Kiyohara, Casey, Nguyen, Tracy   +2 more
core   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source