Results 211 to 220 of about 2,032,836 (280)

Federated training of spiking neural networks on edge hardware for audio processing. [PDF]

Front Neurosci
Kaimal SS, Jb A, Reka SS, Venugopal P.
europepmc   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Attention U-Net with differential privacy in federated learning framework for brain stroke lesion segmentation. [PDF]

Sci Rep
Adhi Siva M, Chowdhary CL.
europepmc   +1 more source

Capacity building in medicines development and regulation in Africa—Overview on recent progress

British Journal of Clinical Pharmacology, EarlyView.
Aims Despite advances in health research and digital innovation, many African countries continue to face substantial resource constraints, fragmented capacity‐building efforts and a shortage of skilled professionals in medicines development and regulatory science.
Tirhani Maluleke, Emile Malan, Michael Reid, Patrick Bouic, Haylene Nell, Goonaseelan Pillai, Catriona Waitt, Bernd Rosenkranz   +7 more
wiley   +1 more source

Intrinsically disordered regions in the NLRP family of receptors act as regulatory hubs for inflammasome condensation and activation. [PDF]

Front Immunol
Nava-Ramírez TB, Cuevas-Velazquez CL, Covarrubias AA, Rudiño-Piñera E, Pérez-Martínez L, Pedraza-Alva G.   +5 more
europepmc   +1 more source

Causality assessment tool for drug‐induced acute kidney injury in patients admitted to intensive care units: Requirements from a multicentre retrospective study in the Netherlands reusing data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Aim This study aimed to provide key requirements for a drug‐induced acute kidney injury (d‐AKI) causality assessment tool (CAT) for intensive care unit (ICU) patients, using vancomycin‐induced AKI (v‐AKI) as a test case. Methods A retrospective review was conducted by medical experts of electronic health records of ICU patients from 14 Dutch ICUs.
Joanna E. Klopotowska, Izak A. R. Yasrebi‐de Kom, Nicolette F. de Keizer, Dave A. Dongelmans, on behalf of the RESCUE Study group, Merijn C. Reuland, Irma M. Rigter, Peter F. Schutte, Ilona T. Spaan, Dorieke van Balen, Stefaan Hendriks, Petronella E. Deetman, Cedric Lau, Wytze J. Vermeijden, Marieke G. J. Schouten, Joost B. Masselink, Peter E. Spronk, Marnix Kuindersma, Hendrikus J. M. van Kan, Anne Wellink, Abraham J. Valkenburg, Andre Wieringa, Walter M. van den Bergh, Maurits H. Renes, Wouter Bult, Frouke M. Engelaer, Nienke van Rein, Martijn Hoeksema, Janneke M. van den Broek, Elsbeth Wesselink, Ilse M. Purmer, Thomas Ottens, Bertha E. Bosma, Sjoerd H. W. van Bree, Barbara Festen, Hendrick J. W. Lammers, Rob J. Bosman, Rogier M. Determann, Eric J. F. Franssen, Attila Karakus, Lenneke. E. M. Haas, Freek van Gorp, Dylan W. de Lange, Maaike A. Sikma, Esther V. Uijtendaal   +44 more
wiley   +1 more source

Computational design of a multi-epitope vaccine against Helicobacter pylori targeting CagA, FliD, urease, and OipA with cholera toxin B subunit (CTB) adjuvant. [PDF]

BMC Microbiol
Baniasadi Nejad N, Shahbazi B, Sarkoohi P, Ahmadi N, Ahmadi K.   +4 more
europepmc   +1 more source

Evidence of Unreliable Data and Poor Data Provenance in Clinical Prediction Model Research and Clinical Practice

Gibson AD, White NM, Collins GS, Barnett AG.   +3 more
europepmc   +1 more source

FedAttn-Credit: attention-augmented federated learning with adaptive differential privacy for rural inclusive finance credit assessment. [PDF]

Sci Rep
Xie Z, Zhang L.
europepmc   +1 more source

Digital solutions in acute medicine: Will electronic health records join up the patient journey (soon?). [PDF]

Future Healthc J
Subbe CP, Kinderlerer A, Jani YH.
europepmc   +1 more source