Sleep-like cortical OFF-periods disrupt causality and complexity in the brain of unresponsive wakefulness syndrome patients [PDF]
Many brain-injured patients retain large cortical islands that are intact, active and reactive but blocked in a state of low complexity, leading to unconsciousness. Here, the authors show that this loss of complexity is due to the pathological engagement
M. Rosanova +14 more
doaj +5 more sources
Outcome Prediction in Unresponsive Wakefulness Syndrome and Minimally Conscious State by Non-linear Dynamic Analysis of the EEG. [PDF]
Objectives: This study aimed to investigate the role of non-linear dynamic analysis (NDA) of the electroencephalogram (EEG) in predicting patient outcome in unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS).
Liu B +7 more
europepmc +4 more sources
Diagnostic Developments in Differentiating Unresponsive Wakefulness Syndrome and the Minimally Conscious State [PDF]
When treating patients with a disorder of consciousness (DOC), it is essential to obtain an accurate diagnosis as soon as possible to generate individualized treatment programs.
Camillo Porcaro +13 more
doaj +3 more sources
Auditory Stimulation Modulates Resting-State Functional Connectivity in Unresponsive Wakefulness Syndrome Patients [PDF]
Passive listening to music is associated with several psychological and physical benefits in both, healthy and diseased populations. In this fMRI study, we examined whether preferred music has effects on the functional connectivity within resting-state ...
Melanie Boltzmann +8 more
doaj +3 more sources
Modulated Neuroprotection in Unresponsive Wakefulness Syndrome after Severe Traumatic Brain Injury [PDF]
Background: We aimed to assess the effects of modulated neuroprotection with intermittent administration in patients with unresponsive wakefulness syndrome (UWS) after severe traumatic brain injury (TBI).
Cristina Daia +8 more
doaj +3 more sources
Intranasal human-recombinant NGF administration improves outcome in children with post-traumatic unresponsive wakefulness syndrome [PDF]
Background Severe traumatic brain injury (TBI) is one of the most dramatic events in pediatric age and, despite advanced neuro-intensive care, the survival rate of these patients remains low.
Antonio Gatto +21 more
doaj +4 more sources
Psychophysiological Effects of Biographical Interventions in People With Unresponsive Wakefulness Syndrome and Minimally Conscious State [PDF]
BackgroundVarious music interventions can evoke favorable behavioral responses or physiological reactions in people with disorders of consciousness (DOC), such as coma, unresponsive wakefulness syndrome (UWS), and minimally conscious state (MCS). However,
Teresa Grimm +7 more
doaj +3 more sources
Whole-brain glucose metabolic pattern differentiates minimally conscious state from unresponsive wakefulness syndrome. [PDF]
The patient being minimally conscious state (MCS) may benefit from wake‐up interventions aimed at improving quality of life and have a higher probability of recovering higher level of consciousness compared to patients with the unresponsive wakefulness ...
Guo K +7 more
europepmc +3 more sources
Nociceptive Response Is a Possible Marker of Evolution in the Level of Consciousness in Unresponsive Wakefulness Syndrome Patients. [PDF]
The Nociception Coma Scale (NCS) and its revised version (NCS-R) were used to evaluate behavioral responses to pain in non-communicative patients. We hypothesized that if patients demonstrate changes to their NCS(-R) scores over time, their evolving ...
Cortese MD +6 more
europepmc +4 more sources
The Role of [<sup>18</sup>F]FDG PET Imaging for the Assessment of Vegetative State or Unresponsive Wakefulness Syndrome: A Systematic Review. [PDF]
Background: Different evidence on the ability of [18F] fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) imaging to assess patients in the vegetative state (VS) or unresponsive wakefulness syndrome (UWS) has been reported.
Dondi F +8 more
europepmc +4 more sources

