Results 41 to 50 of about 2,381 (143)

The vegetative state/unresponsive wakefulness syndrome: a systematic review of prevalence studies [PDF]

European Journal of Neurology, 2014
One of the worst outcomes of acquired brain injury is the vegetative state, recently renamed ‘unresponsive wakefulness syndrome’ (VS/UWS). A patient in VS/UWS shows reflexive behaviour such as spontaneous eye opening and breathing, but no signs of awareness of the self or the environment.
van Erp, W.S., van Erp, W.S., Lavrijsen, J.C., van de Laar, F.A., Vos, P.E., Laureys, S., Koopmans, R.T.   +6 more
openaire   +3 more sources

Patients with unresponsive wakefulness syndrome respond to the pain cries of other people [PDF]

Neurology, 2013
Recent publications show that using imagery instructions, brain activation patterns indicating consciousness can be found in approximately 10% of patients with unresponsive wakefulness syndrome (UWS; previously called vegetative state). It is possible, however, that patients who cannot follow instructions (because of limited memory/attention capacities,
Tao, Yu, Simone, Lang, Dominik, Vogel, Alexandra, Markl, Friedemann, Müller, Boris, Kotchoubey   +5 more
openaire   +4 more sources

Detecting Brain Activity Following a Verbal Command in Patients With Disorders of Consciousness

Frontiers in Neuroscience, 2019
BackgroundThe accurate assessment of patients with disorders of consciousness (DOC) is a challenge to most experienced clinicians. As a potential clinical tool, functional magnetic resonance imaging (fMRI) could detect residual awareness without the need
Fuyan Wang, Fuyan Wang, Nantu Hu, Xiaohua Hu, Xiaohua Hu, Shan Jing, Lizette Heine, Lizette Heine, Aurore Thibaut, Wangshan Huang, Yifan Yan, Jing Wang, Caroline Schnakers, Caroline Schnakers, Steven Laureys, Haibo Di   +15 more
doaj   +1 more source

Conscious processing of global and local auditory irregularities causes differentiated heartbeat-evoked responses

eLife, 2023
Recent research suggests that brain-heart interactions are associated with perceptual and self-consciousness. In this line, the neural responses to visceral inputs have been hypothesized to play a leading role in shaping our subjective experience.
Diego Candia-Rivera, Federico Raimondo, Pauline Pérez, Lionel Naccache, Catherine Tallon-Baudry, Jacobo D Sitt   +5 more
doaj   +1 more source

Detecting passive and active response in patients with behaviourally diagnosed unresponsive wakefulness syndrome

Neuroscience Research, 2023
The diagnosis of unresponsive wakefulness syndrome depends mostly on the motor response following verbal commands. However, there is a potential for misdiagnosis in patients who understand verbal commands (passive response) but cannot perform voluntary movements (active response).
Yoji, Okahara, Kouji, Takano, Kenichi, Odaka, Yoshio, Uchino, Kenji, Kansaku   +4 more
openaire   +2 more sources

The Neural Correlates of Consciousness: A Spectral Exponent Approach to Diagnosing Disorders of Consciousness

Brain Sciences
Background/Objectives: Disorder of consciousness (DoC) poses diagnostic challenges due to behavioral assessment limitations. This study evaluates the spectral exponent (SE)—a neurophysiological biomarker quantifying the decay slope of ...
Ying Zhao, Anqi Wang, Weiqiao Zhao, Nantu Hu, Steven Laureys, Haibo Di   +5 more
doaj   +1 more source

Dynamic Patterns of Global Brain Communication Differentiate Conscious From Unconscious Patients After Severe Brain Injury

Frontiers in Systems Neuroscience, 2021
The neurophysiology of the subjective sensation of being conscious is elusive; therefore, it remains controversial how consciousness can be recognized in patients who are not responsive but seemingly awake.
Daniel Golkowski, Daniel Golkowski, Rebecca Willnecker, Jennifer Rösler, Andreas Ranft, Gerhard Schneider, Denis Jordan, Rüdiger Ilg, Rüdiger Ilg   +8 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Seizure relapse in new onset epilepsy: It is not always drug resistance

Epilepsia, EarlyView.
Abstract Objective Seizure recurrence in new onset epilepsy (NOE) can result from various factors. Although drug ineffectiveness is frequently investigated, other causes—such as nonadherence, inadequate treatment, nonepileptic events (e.g., functional/dissociative), or acute symptomatic seizures—also impact patient outcomes.
Cecilia Catania, Eric Menetre, Aikaterini Fitsiori, Felix Tobias Kurz, Gabriela Moreno Legast, Serge Vulliemoz, Mathieu Genoud, Pierre Mégevand, Roland Wiest, Fabienne Picard, Sandor Beniczky, Margitta Seeck   +11 more
wiley   +1 more source

Homeostatic plasticity in patients with disorders of consciousness detected by combined stimulation: a study protocol

Frontiers in Neurology
BackgroundNon-invasive neuromodulation (NIN) techniques have been widely utilized in treating patients with disorders of consciousness (DoC), but their therapeutic effects have been inconsistent.
Jingwen Wang, Jingwen Wang, Fangfang Shou, Qiuyi Yu, Xulan Lu, Yuwen Wan, Yuwen Wan, Wangshan Huang, Nantu Hu, Zhenyi Jin, Xinru Shan, Steven Laureys, Steven Laureys, Haibo Di   +13 more
doaj   +1 more source