Results 61 to 70 of about 1,169,060 (152)

Advances in the neurorehabilitation of severe disorder of consciousness

Annali dell'Istituto Superiore di Sanità, 2014
Introduction. The paper describes the evolution of knowledge concerning severe brain injury which determines the Vegetative State/Unresponsive Wakefulness Syndrome. Background. The term Vegetative State was proposed by Jennet and Plum in 1972.
Giuliano Dolce, Lucia Francesca Lucca, Francesco Riganello, Francesco Arcuri, Maria Quintieri, Maria Daniela Cortese, Loris Pignolo   +6 more
doaj   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Perception of diagnosis by family caregivers in severe brain injury patients in China

BMC Palliative Care
Objectives Surrogate decision-making by family caregivers for patients with severe brain injury is influenced by the availability and understanding of relevant information and expectations for future rehabilitation. We aimed to compare the consistency of
Yifan Yan, Meiqi Li, Jitka Annen, Wangshan Huang, Tiantian Cai, Xueying Wang, Xiaohua Hu, Steven Laureys, Haibo Di   +8 more
doaj   +1 more source

Hitting and missing on consciousness

Psychiatry and Clinical Neurosciences, EarlyView.
Disturbances of conscious experience are central features of many psychiatric and mental health disorders. Experimental studies of conscious perception are therefore increasingly cited in clinical and translational work under the assumption that they identify neural mechanisms specific to subjective experience.
Tomoya Nakamura, Matthias Michel, Hakwan Lau   +2 more
wiley   +1 more source

Hypersomnia associated with bilateral posterior hypothalamic lesion - A polysomnographic case study [PDF]

, 2003
We examined an obese 58-year-old patient with a bilateral posterior hypothalamic lesion of unknown etiology. A 24-hour polysomnography revealed a markedly increased total sleep time (17.6 h). During daytime, only 3 continuous wake phases occurred.
Uttner, I., Helmchen, C., Kleine, J., Eisensehr, Ilonka, Seelos, Klaus, Schlippenbach, C. von, Noachtar, S.   +6 more
core   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

The Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu, Eduardo Bravo, George Bradley Richerson   +2 more
wiley   +1 more source

Neural Circuit Mechanisms of Disorders of Consciousness and Potential Therapeutic Targets of Brain Stimulation

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This review integrates three hierarchical frameworks—ascending reticular activating system (ARAS), mesocircuit hypothesis, and intrinsic connectivity networks (ICNs)—to update the neural mechanisms of disorders of consciousness (DoC). We highlight emerging evidence for glutamatergic ARAS pathways, a bidirectional GPi–GPe mesocircuit regulating ...
Yichen Zhou, Tianqing Cao, Sipeng Zhu, Qiheng He, Yitong Jia, Xiaoke Chai, Nan Wang, Yi Yang   +7 more
wiley   +1 more source

Living with unresponsive wakefulness syndrome Long-term care of patients with unresponsive wakefulness syndrome

, 2018
Kurzfassung Diese Arbeit setzt sich mit der Langzeitpflege von WachkomapatientInnen auseinander. Es wird ein Überblick über das Krankheitsbild des Wachkomas, deren Symptome und Auswirkungen auf die Wahrnehmung der betroffenen Person vermittelt.
Jusufi, Medina
core   +2 more sources

cEEG and rEEG detection rates of prognostic indicators in cardiac arrest patients: a systematic review and diagnostic meta-analysis

Frontiers in Neurology
IntroductionAccurate neuroprognostication following cardiac arrest is essential for clinical decision-making; however, the comparative diagnostic performance of continuous electroencephalography (cEEG) and routine electroencephalography (rEEG) remains ...
Jiayi Lin, Jiayi Lin, Jiayi Lin, Zhonghao Ji, Zhonghao Ji, Zhonghao Ji, Xue Lin, Xue Lin, Xue Lin, Yihan Yan, Yihan Yan, Yihan Yan, Tianbo Zheng, Hanyang Zhang, Yiting Wu, Yuru Wang, Zihan Yu, Haibo Di, Haibo Di, Nantu Hu, Nantu Hu   +20 more
doaj   +1 more source

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

Epilepsia, Volume 67, Issue 9, Page 4758-4773, September 2026.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni, Karine Brochu, Paolo Federico, Walter Hader, Julia W. Y. Kam, Fady Girgis   +5 more
wiley   +1 more source