Results 71 to 80 of about 4,808 (181)
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Advances in the neurorehabilitation of severe disorder of consciousness
Annali dell'Istituto Superiore di Sanità, 2014 Introduction. The paper describes the evolution of knowledge concerning severe brain injury which determines the Vegetative State/Unresponsive Wakefulness Syndrome. Background. The term Vegetative State was proposed by Jennet and Plum in 1972.
Giuliano Dolce +6 more
doaj +1 more source
Epilepsia Open, EarlyView.Abstract Objective Ketogenic dietary therapies (KDTs) are the treatment of choice for Glut1 Deficiency Syndrome (Glut1DS), providing dietary ketones as an alternative fuel to the brain and effectively controlling seizures. Recent evidence indicates insufficient seizure control in Glut1DS patients despite adequate KDT and ketosis.
Joerg Klepper, Eva Runkel, Lucia Kiesel
wiley +1 more source
Frontiers in NeurologyBackgroundNon-invasive neuromodulation (NIN) techniques have been widely utilized in treating patients with disorders of consciousness (DoC), but their therapeutic effects have been inconsistent.
Jingwen Wang +13 more
doaj +1 more source
Loss of consciousness is related to hyper-1 correlated gamma-band activity in anesthetized macaques and sleeping humans [PDF]
, 2017 Loss of consciousness can result from a wide range of causes, including natural sleep and pharmacologically induced anesthesia. Important insights might thus come from identifying neuronal mechanisms of loss and re-emergence of consciousness independent ...
Barrett, Adam +5 more
core +1 more source
Brain and Behavior, Volume 16, Issue 5, May 2026.Chronic inflammatory demyelinating polyneuropathy is an autoimmune disorder causing demyelination, leading to distal weakness, sensory loss, and autonomic dysfunction. Immune activation triggers macrophage‐mediated myelin damage and conduction failure.
Ayesha Khan +11 more
wiley +1 more source
Exploring end-of-life decision-making in China for disorders of consciousness
Annals of MedicineObjectives We aim to investigate the ethical attitudes of the Chinese population toward withdrawal of life-sustaining treatment (WLST) in disorders of consciousness (DoC) patients.Methods A self-administered questionnaire concerning WLST was distributed ...
Meiqi Li +8 more
doaj +1 more source
Feasibility of the music therapy assessment tool for awareness in disorders of consciousness (MATADOC) for use with pediatric populations [PDF]
, 2015 Measuring responsiveness to gain accurate diagnosis in populations with disorders of consciousness (DOC) is of central concern because these patients have such complex clinical presentations.
Alvin Moyer +2 more
core +2 more sources
CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.This study provides the first experimental evidence of a novel transnasal ventral brainstem epidural electrical stimulation approach in anesthetized sheep and demonstrates that this procedure can induce behavioral arousal and cortical electrophysiological changes toward a wake‐like state, holding promise for the treatment of chronic disorders of ...
Bin Liu +14 more
wiley +1 more source
Comprehensive Physiology, Volume 16, Issue 2, April 2026.Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu +11 more
wiley +1 more source