Results 81 to 90 of about 1,169,060 (152)

Symptomatic treatment of unresponsive wakefulness syndrome with transcranially focused extracorporeal shock waves

NeuroRehabilitation: An International, Interdisciplinary Journal, 2014
Objective: Can stimulation of nerve growth factors by focused transcranial extracorporeal shock wave therapy (TESWT) be made effective for persons within unresponsive wakefulness syndrome (apallic syndrome)? Design: Between eight and ...
H, Lohse-Busch, U, Reime, R, Falland
openaire   +3 more sources

Clobazam to preserve meaningful engagement in prolonged disorder of consciousness with concurrent seizure disorder

PM&R, EarlyView.
Tatiana Bernstein, Zachary Miklja, Tiffany Wood, Joshua Startup   +3 more
wiley   +1 more source

The Meaning of Pain in the Clinical Management of Patients With Disorders of Consciousness: Is It a Neglected Issue?

European Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background Pain is a critical yet frequently underestimated component in the care of patients with acquired brain injury (ABI) and disorders of consciousness (DoC). Because these individuals often lack the ability to communicate verbally or purposefully, clinicians face substantial challenges in recognizing and managing pain, despite its ...
Marianna Contrada, Giovanni Morone, Rocco Salvatore Calabrò, Federica Scarfone, Maria Elena Pugliese, Morena De Francesco, Chiara Milasi, Domenico Bosco, Maria Daniela Cortese, Lucia Francesca Lucca, Antonio Cerasa, Irene Ciancarelli, Francesco Riganello   +12 more
wiley   +1 more source

Can I Get a Witness? The Ethical Dimensions of Family Presence in Patient Suffering

Hastings Center Report, Volume 56, Issue 4, Page 19-24, July–August 2026.
Abstract For patients who are suffering, the bedside presence of a family member can provide comfort, and many people hold that there is moral value in being present with a conscious, suffering patient. Yet what is the moral significance of the absence of family members when a patient is minimally conscious or unconscious and not aware of their absence?
Jennifer Blumenthal‐Barby, Trevor M. Bibler, Holland Kaplan, Adam Omelianchuk, Joanna Smolenski   +4 more
wiley   +1 more source

”Not always the magic bullet”—Insufficient seizure control by ketogenic dietary therapies in Glut1 Deficiency Syndrome

Epilepsia Open, Volume 11, Issue 3, Page 847-858, June 2026.
Abstract Objective Ketogenic dietary therapies (KDTs) are the treatment of choice for Glut1 Deficiency Syndrome (Glut1DS), providing dietary ketones as an alternative fuel to the brain and effectively controlling seizures. Recent evidence indicates insufficient seizure control in Glut1DS patients despite adequate KDT and ketosis.
Joerg Klepper, Eva Runkel, Lucia Kiesel
wiley   +1 more source

Behavioral and electrophysiological effects of network-based frontoparietal tDCS in patients with severe brain injury: A randomized controlled trial

NeuroImage: Clinical, 2020
Background: Transcranial direct current stimulation (tDCS) may promote the recovery of severely brain-injured patients with disorders of consciousness (DOC).
Géraldine Martens, Eleni Kroupi, Yelena Bodien, Gianluca Frasso, Jitka Annen, Helena Cassol, Alice Barra, Charlotte Martial, Olivia Gosseries, Nicolas Lejeune, Aureli Soria-Frisch, Giulio Ruffini, Steven Laureys, Aurore Thibaut   +13 more
doaj   +1 more source

Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment

Exploration, Volume 6, Issue 3, June 2026.
This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng, Wangzheqi Zhang, Jun Chen, Huang Wu, Lei Wu, Yanhao Qiu, Xiaoming Deng, Chenglong Zhu, Yisheng Chen, Zhijie Zhao, Changli Wang, Xiaomin Zhang   +11 more
wiley   +1 more source

Clinical and Genetic Characterization of Inherited NPRL3 Splice Variants in Two Patients With Epilepsy

Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.
This study identifies two novel inherited NPRL3 splice variants in Chinese pediatric patients with focal epilepsy, revealing significant genetic heterogeneity, incomplete penetrance, and phenotypic variability that underscores the importance of tailored antiepileptic management.
Shouxing Wang, Jihua Wu, Conglei Song, Yuanzhi He, Zhongli Zhao, Bin Yang   +5 more
wiley   +1 more source

Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine [PDF]

, 2012
Loss of sleep causes an increase in sleep drive and deficits in hippocampal-dependent memory. Both of these responses are thought to require activation of adenosine A1 receptors (adorA1Rs) and release of transmitter molecules including ATP, which is ...
Schmitt, L. Ian, R. E. Sims, Sims, Robert E., P. G. Haydon, Dale, Nicholas, Sims, Robert, Haydon, Philip G, L. I. Schmitt, N. Dale, Schmitt, L Ian   +9 more
core   +1 more source

Corrigendum: Estimating the Minimal Number of Repeated Examinations for Random Responsiveness With the Coma Recovery Scale—Revised as an Example

Frontiers in Integrative Neuroscience, 2021
Hao Yang, Chengyin Ye, Xiaochen Liu, Lingxiu Sun, Anqi Wang, Jing Wang, Nantu Hu, Xiaohua Hu, Olivia Gosseries, Steven Laureys, Haibo Di, Jiqian Fang   +11 more
doaj   +1 more source