Results 51 to 60 of about 2,381 (143)

Advances in the neurorehabilitation of severe disorder of consciousness

Annali dell'Istituto Superiore di Sanità, 2014
Introduction. The paper describes the evolution of knowledge concerning severe brain injury which determines the Vegetative State/Unresponsive Wakefulness Syndrome. Background. The term Vegetative State was proposed by Jennet and Plum in 1972.
Giuliano Dolce, Lucia Francesca Lucca, Francesco Riganello, Francesco Arcuri, Maria Quintieri, Maria Daniela Cortese, Loris Pignolo   +6 more
doaj   +1 more source

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

Epilepsia, EarlyView.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni, Karine Brochu, Paolo Federico, Walter Hader, Julia W. Y. Kam, Fady Girgis   +5 more
wiley   +1 more source

Exploring end-of-life decision-making in China for disorders of consciousness

Annals of Medicine
Objectives We aim to investigate the ethical attitudes of the Chinese population toward withdrawal of life-sustaining treatment (WLST) in disorders of consciousness (DoC) patients.Methods A self-administered questionnaire concerning WLST was distributed ...
Meiqi Li, Benedetta Cecconi, Olivia Gosseries, Lijuan Cheng, Yifan Yan, Yan Chen, Yan Li, Steven Laureys, Haibo Di   +8 more
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Perception of diagnosis by family caregivers in severe brain injury patients in China

BMC Palliative Care
Objectives Surrogate decision-making by family caregivers for patients with severe brain injury is influenced by the availability and understanding of relevant information and expectations for future rehabilitation. We aimed to compare the consistency of
Yifan Yan, Meiqi Li, Jitka Annen, Wangshan Huang, Tiantian Cai, Xueying Wang, Xiaohua Hu, Steven Laureys, Haibo Di   +8 more
doaj   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

The Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu, Eduardo Bravo, George Bradley Richerson   +2 more
wiley   +1 more source

The diagnostic and prognostic value of auditory statistical learning ability in patients with disorders of consciousness

Frontiers in Neurology
IntroductionAccurate assessment of residual cognition in patients with disorders of consciousness (DoC) remains challenging due to their limited behavioral responsiveness.
Mingyan Yu, Mingyan Yu, Xiangyue Xiao, Xiangyue Xiao, Junhua Ding, Mengying Zhao, Mengying Zhao, Sara Cruz, Nantu Hu, Nantu Hu, Mingwei Zhang, Mingwei Zhang, Steven Laureys, Steven Laureys, Steven Laureys, Haibo Di, Haibo Di, Yan Chen, Yan Chen   +18 more
doaj   +1 more source

Cognitive Motor Dissociation in Disorders of Consciousness: An Individual Participant Data Meta‐Analysis

European Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Introduction In patients with disorders of consciousness (DoC), behavioral assessment often underestimates awareness when motor output is absent or unreliable. Cognitive motor dissociation (CMD) refers to patients who appear unresponsive but demonstrate volitional brain responses during neurodiagnostic tests.
Poul P. Laigaard, Fawzi W. Abla, Melika Hassani, Anna Kristina Eigenbrodt, Daniel Kondziella   +4 more
wiley   +1 more source

cEEG and rEEG detection rates of prognostic indicators in cardiac arrest patients: a systematic review and diagnostic meta-analysis

Frontiers in Neurology
IntroductionAccurate neuroprognostication following cardiac arrest is essential for clinical decision-making; however, the comparative diagnostic performance of continuous electroencephalography (cEEG) and routine electroencephalography (rEEG) remains ...
Jiayi Lin, Jiayi Lin, Jiayi Lin, Zhonghao Ji, Zhonghao Ji, Zhonghao Ji, Xue Lin, Xue Lin, Xue Lin, Yihan Yan, Yihan Yan, Yihan Yan, Tianbo Zheng, Hanyang Zhang, Yiting Wu, Yuru Wang, Zihan Yu, Haibo Di, Haibo Di, Nantu Hu, Nantu Hu   +20 more
doaj   +1 more source