Results 51 to 60 of about 1,169,060 (152)

Detecting Brain Activity Following a Verbal Command in Patients With Disorders of Consciousness

Frontiers in Neuroscience, 2019
BackgroundThe accurate assessment of patients with disorders of consciousness (DOC) is a challenge to most experienced clinicians. As a potential clinical tool, functional magnetic resonance imaging (fMRI) could detect residual awareness without the need
Fuyan Wang, Fuyan Wang, Nantu Hu, Xiaohua Hu, Xiaohua Hu, Shan Jing, Lizette Heine, Lizette Heine, Aurore Thibaut, Wangshan Huang, Yifan Yan, Jing Wang, Caroline Schnakers, Caroline Schnakers, Steven Laureys, Haibo Di   +15 more
doaj   +1 more source

Conscious processing of global and local auditory irregularities causes differentiated heartbeat-evoked responses

eLife, 2023
Recent research suggests that brain-heart interactions are associated with perceptual and self-consciousness. In this line, the neural responses to visceral inputs have been hypothesized to play a leading role in shaping our subjective experience.
Diego Candia-Rivera, Federico Raimondo, Pauline Pérez, Lionel Naccache, Catherine Tallon-Baudry, Jacobo D Sitt   +5 more
doaj   +1 more source

Detecting passive and active response in patients with behaviourally diagnosed unresponsive wakefulness syndrome

Neuroscience Research, 2023
The diagnosis of unresponsive wakefulness syndrome depends mostly on the motor response following verbal commands. However, there is a potential for misdiagnosis in patients who understand verbal commands (passive response) but cannot perform voluntary movements (active response).
Yoji, Okahara, Kouji, Takano, Kenichi, Odaka, Yoshio, Uchino, Kenji, Kansaku   +4 more
openaire   +2 more sources

The Neural Correlates of Consciousness: A Spectral Exponent Approach to Diagnosing Disorders of Consciousness

Brain Sciences
Background/Objectives: Disorder of consciousness (DoC) poses diagnostic challenges due to behavioral assessment limitations. This study evaluates the spectral exponent (SE)—a neurophysiological biomarker quantifying the decay slope of ...
Ying Zhao, Anqi Wang, Weiqiao Zhao, Nantu Hu, Steven Laureys, Haibo Di   +5 more
doaj   +1 more source

Dynamic Patterns of Global Brain Communication Differentiate Conscious From Unconscious Patients After Severe Brain Injury

Frontiers in Systems Neuroscience, 2021
The neurophysiology of the subjective sensation of being conscious is elusive; therefore, it remains controversial how consciousness can be recognized in patients who are not responsive but seemingly awake.
Daniel Golkowski, Daniel Golkowski, Rebecca Willnecker, Jennifer Rösler, Andreas Ranft, Gerhard Schneider, Denis Jordan, Rüdiger Ilg, Rüdiger Ilg   +8 more
doaj   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Homeostatic plasticity in patients with disorders of consciousness detected by combined stimulation: a study protocol

Frontiers in Neurology
BackgroundNon-invasive neuromodulation (NIN) techniques have been widely utilized in treating patients with disorders of consciousness (DoC), but their therapeutic effects have been inconsistent.
Jingwen Wang, Jingwen Wang, Fangfang Shou, Qiuyi Yu, Xulan Lu, Yuwen Wan, Yuwen Wan, Wangshan Huang, Nantu Hu, Zhenyi Jin, Xinru Shan, Steven Laureys, Steven Laureys, Haibo Di   +13 more
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Exploring end-of-life decision-making in China for disorders of consciousness

Annals of Medicine
Objectives We aim to investigate the ethical attitudes of the Chinese population toward withdrawal of life-sustaining treatment (WLST) in disorders of consciousness (DoC) patients.Methods A self-administered questionnaire concerning WLST was distributed ...
Meiqi Li, Benedetta Cecconi, Olivia Gosseries, Lijuan Cheng, Yifan Yan, Yan Chen, Yan Li, Steven Laureys, Haibo Di   +8 more
doaj   +1 more source