Results 111 to 120 of about 64,340 (207)

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

Carbonylative Aminative Suzuki-Miyaura Coupling: Pd-Catalyzed Synthesis of Amides from Vinyl/Aryl Halides and Boronic Acids. [PDF]

J Am Chem Soc
Zhou J, Raykowski D, Kowalski Z, Li S, Ping Y, Luo Y, Kwan EE, Liu RY.   +7 more
europepmc   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Degradation Law of Mechanical Properties and Long-Term Compressive Strength Prediction Model of Unsaturated Polyester Resin Concrete in Aqueous Environments. [PDF]

Polymers (Basel)
Li W, Wen F, Han B, Cao W, Liu K.
europepmc   +1 more source

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Migration of Vapor Molecules in Soils. [PDF]

Molecules
Kudryashova O, Gruznov V, Kikhtenko A, Vorozhtsov A.   +3 more
europepmc   +1 more source

Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis

Advanced Science, EarlyView.
OSMR mutations disrupt STAT5 signaling and AKR1B10‐mediated lipid metabolism, leading to lipid accumulation and protein aggregation in keratinocytes. This metabolic reprogramming drives amyloid deposition in primary localized cutaneous amyloidosis, revealing a mechanistic link between lipid dysregulation and amyloidogenesis.
Huiting Liu, Wen Zheng, Chao Yang, Tao Yang, Qiuyu Chen, Ping Lu, Huan Yang, Jun Liu, Bin Yang   +8 more
wiley   +1 more source

Electron Transport in Quantum Dot Light‐Emitting Diodes

Advanced Electronic Materials, EarlyView.
This work reveals that electron transport in core/multi‐shell quantum dots is severely hindered by traps located at the core‐shell interface. These traps follow a Gaussian energy distribution with a density of approximately 1023 m−3 and a common energy level of 4.0 eV below the vacuum level.
Shuxin Li, Wenxin Lin, Min Zheng, Xiongfeng Lin, Yulin Guo, Longjia Wu, Quan Niu, Paul W. M. Blom, Yuguang Ma   +8 more
wiley   +1 more source

Single-atom Cu catalyst in a zirconium MOF for highly selective hydrogenation of unsaturated aldehydes to unsaturated alcohols. [PDF]

Chem Sci
Wu Y, Luo Y, Ding M, Zheng A.
europepmc   +1 more source

Coexistence of Large Nernst Effect and Axis‐Dependent Conduction Polarity in Semimetal MoSi2

Advanced Electronic Materials, EarlyView.
MoSi2${\rm MoSi}_2$ is a rare material in which axis‐dependent conduction polarity (ADCP) and a large ordinary Nernst effect (ONE) coexist. The pronounced ONE (199μVK−1$199\,\umu \mathrm {V}\,\mathrm {K}^{-1}$) originates from nearly perfect carrier compensation, high mobility, and likely phonon drag, while ADCP arises from mixed‐dimensionality of the ...
Orest Pavlosiuk, Maciej J. Winiarski
wiley   +1 more source