Results 41 to 50 of about 54,799 (219)

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

Ischemia-Related Lesion Characteristics in Patients With Stable or Unstable Angina [PDF]

, 1995
Background Postmortem-derived findings support the common beliefs that lipid-rich coronary plaques with a thin, fibrous cap are prone to rupture and that rupture and superimposed thrombosis are the primary mechanisms causing acute coronary syndromes.
Baptista da Silva, J.M.P. (José), Escaned, J. (Javier), Feyter, P.J. (Pim) de, Jaegere, P.P.T. (Peter) de, Mario, C. (Carlo) di, Ozaki, Y. (Yukio), Roelandt, J.R.T.C. (Jos), Serruys, P.W.J.C. (Patrick)   +7 more
core  

OCT‐Guided Distal Left Main Bifurcation PCI: Mid‐Term Outcomes From a Multicenter South‐Asian Registry

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Optical coherence tomography (OCT)‐guided percutaneous coronary intervention (PCI) enhances treatment of complex coronary artery lesions, including left main (LM) disease, by enabling lesion morphology assessment and stent optimization, thereby reducing major adverse cardiac events (MACE).
Prathap Kumar, Shaneez Najmy, Manu Rajendran, Ali Shafeeq, Blessvin Jino   +4 more
wiley   +1 more source

Comparison of the prevalence of enteroviruses in blood samples of patients with and without unstable angina

ARYA Atherosclerosis, 2017
BACKGROUND: Although the role of enteroviruses has been proved in heart diseases, extensive information is not available on the association between enteroviruses and unstable angina.
Aida Gholoobi, Zahra Meshkat, Akram Baghani, Maryam Sadat Alavi, Toktam Mohamadpoor, Mastoureh Momen-Heravi, Mohsen Mouhebati, Samaneh Sepahi, Sina Rostami, Mojtaba Meshkat, Arash Gholoobi   +10 more
doaj  

Coronary angioplasty early after diagnosis of unstable angina [PDF]

, 1987
Coronary angioplasty (PTCA) was performed early after diagnosis of unstable angina in 71 patients who responded favorably with initial pharmacologic treatment and who also had persistent exertional angina. The patients selected for PTCA had predominantly
Beatt, K.J. (Kevin), Brand, M.J.B.M. (Marcel) van den, Feyter, P.J. (Pim) de, Serruys, P.W.J.C. (Patrick), Suryapranata, H. (Harry)   +4 more
core   +1 more source

Elevated Hemoglobin Levels and Risk of ST‐Segment Elevation Myocardial Infarction in High‐Altitude Acute Coronary Syndrome: A Retrospective Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background High‐altitude populations typically exhibit elevated hemoglobin (Hb) levels due to chronic hypoxic exposure; however, the impact of this elevation on the risk of ST‐segment elevation myocardial infarction (STEMI) remains unclear. Existing evidence is primarily derived from low‐altitude populations and cannot be directly extrapolated
Jing Li, Lin‐Feng Liu, Gusang Lamu, Yang Jin, Gesang Gawa, Zhen‐Long Chang, Xiao‐Xia Liu, Zhen‐Zhong Yang, Gesang Luobu, Baima Lamu, Dawa Ciren   +10 more
wiley   +1 more source

Short-term and long-term outcomes in 133 429 emergency patients admitted with angina or myocardial infarction in Scotland, 1990-2000: population-based cohort study [PDF]

, 2006
Objective: To analyse short- and long-term outcomes and prognostic factors in a large population-based cohort of unselected patients with a first emergency admission for suspected acute coronary syndrome between 1990 and 2000 in Scotland. Methods: All
Boyd, J., Capewell, S., Chalmers, J.W.T., Finlayson, A., Frame, S., MacIntyre, K., McMurray, J.J.V., Murphy, N.F., Redpath, A., Stewart, S.   +9 more
core   +2 more sources

Treatment of Coronary Perforation in a Bifurcation: Two‐Stent Strategies With Fenestrated Covered Stents

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Coronary perforations are a dreaded complication for any interventional cardiologist. The treatment of this complication is exceptionally difficult when it occurs in a coronary bifurcation. While a conservative approach or a balloon occlusion might be sufficient in some cases, additional treatment is sometimes necessary.
Jakob U. Lindner, Janine Pöss, Holger Thiele, Dmitry S. Sulimov   +3 more
wiley   +1 more source

Reduced plasma adiponectin levels relative to oxidized low density lipoprotein and nitric oxide in coronary artery disease patients

Clinics, 2011
INTRODUCTION: Adiponectin is a circulating hormone that is produced exclusively by adipocytes and has antiinflammatory and anti-atherogenic properties. The hypothesis that there are differences in adiponectin levels between stable and unstable coronary ...
Gholam Basati, Morteza Pourfarzam, Ahmad Movahedian, Saed Ziaaldin Samsamshariat, Nizal Sarrafzadegan   +4 more
doaj   +1 more source

Impact of diabetes mellitus on long-term outcome after unstable angina and non-ST-segment elevation myocardial infarction treated with a very early invasive strategy [PDF]

, 2018
Aims/hypothesis: We sought to evaluate the impact of diabetes mellitus on long-term outcome in patients with unstable angina and non-ST-segment elevation myocardial infarction treated with a very early invasive strategy.
Büttner, H., Ferenc, M., Müller, C., Neumann, F., Perruchoud, A.   +4 more
core