Results 31 to 40 of about 815,331 (254)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Boundary Layer Variations and Convective Regimes during UNSTABLE, 2008 [PDF]

open access: yes, 2015
UNSTABLE was a field project in the summer of 2008 to better understand the large-scale and mesoscale forcings of summer storms. This thesis objective is to better understand boundary layer characteristics and convective environments in the Alberta ...
Dyck, Robyn
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Trends in Deforestation as a Response to Management Regimes and Policy Intervention in the Hindu Kush Himalaya of Pakistan

open access: yesFrontiers in Environmental Science, 2022
Based on the annual rate of deforestation as a forest conservation outcome, this study evaluated how effective is the existing forest management regime in controlling deforestation in the study area.
Adnan Ahmad   +9 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Regime dependent instability as a transition mechanism in large-scale atmospheric flow

open access: yesAnnals of Geophysics, 2000
Two apparently distinct approaches to studying the observed low frequency variability in the atmosphere have evolved over the past few years. One approach invokes multiple, recurrent flow regimes to explain the observed variability.
I. Bordi
doaj   +1 more source

Entanglement of stationary states in the presence of unstable quasiparticles

open access: yesJournal of High Energy Physics, 2023
The effect of unstable quasiparticles in the out-of-equilibrium dynamics of certain integrable systems has been the subject of several recent studies.
Dávid X. Horváth   +2 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Observing Rayleigh–Taylor Stable and Unstable Accretion Through a Kalman Filter Analysis of X-Ray Pulsars in the Small Magellanic Cloud

open access: yesThe Astrophysical Journal
Global, three-dimensional magnetohydrodynamic simulations of Rayleigh–Taylor instabilities at the disk–magnetosphere boundary of rotating, magnetized compact stellar objects reveal that accretion occurs in three regimes: the stable regime, the chaotic ...
Joseph O’Leary   +7 more
doaj   +1 more source

Atmospheric Boundary Layer Stability in Urban Beijing: Insights from Meteorological Tower and Doppler Wind Lidar

open access: yesRemote Sensing
The limited understanding of the structure of the urban surface atmospheric boundary layer can be attributed to its inherent complexity, as well as a deficiency in comprehensive measurements.
Linlin Wang   +8 more
doaj   +1 more source

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