Patient Preferences in Neuromuscular Diseases: Insights for Future Drug Development
JIMD Reports, Volume 67, Issue 4, July 2026.ABSTRACT Incorporating patient preferences into drug development is crucial, particularly, for rare diseases with significant unmet needs. This study used Best‐Worst Scaling type 2 (BWS‐2) to explore benefit–risk trade‐offs for patients and caregivers in two rare neuromuscular diseases (NMDs), myotonic dystrophy type 1 (DM1), and mitochondrial myopathy
Aura Cecilia Jimenez‐Moreno +10 more
wiley +1 more source
Large Eddy Simulations of the Atmospheric Boundary Layer Over Satellite‐Sensed Sea Ice Maps
Journal of Geophysical Research: Atmospheres, Volume 131, Issue 11, 16 June 2026.Abstract Surface heterogeneity in the marginal ice zone (MIZ) causes multiscale secondary atmospheric circulations that are challenging to model or observe. The absence or inadequate representation of these circulations in ocean‐atmosphere exchange schemes in climate models is partially responsible for the underestimation of Arctic sea ice loss ...
Joseph Fogarty +5 more
wiley +1 more source
Unsteady flow effects on droplets and spheres : breakup and unsteady flow topology
This thesis presents a set of experimental studies proposed to study the phenomena of droplet breakup and the unsteady flow topology and dynamics of a sphere. In particular, droplet breakup will be studied when exposed to the flow of an approaching airfoil in the environment of the stagnation line.
openaire +2 more sources
From Lotic to Lentic: SWOT Characterizes Seasonal Hydrodynamics in the Lake‐River Continuum
Geophysical Research Letters, Volume 53, Issue 11, 16 June 2026.Abstract The interface between rivers and lakes forms a unique hydraulic continuum, in which lotic and lentic regimes dynamically interact and transition between each other. A common expression of this lake‐river continuum (LARIC) is reservoir backwater, where water surface gradually rises from the reservoir pool upstream to the free‐flowing river ...
Xinchen He +7 more
wiley +1 more source
AbstractIn Chapter 12 unsteady pipe flow is discussed by means of the method of characteristics for which the underlying basic equations are derived at first. These are the continuity and energy equations according to Alliévi and their solutions by Riemann as well as the unsteady momentum equation.
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Unsteady Aerodynamics in Bio-Inspired Flapping Wings for Low-Density Environments. [PDF]
Biomimetics (Basel)Prisăcariu EG +8 more
europepmc +1 more source
Geophysical Research Letters, Volume 53, Issue 11, 16 June 2026.Abstract We present the first in situ observations of the full turbulence tensor of free convection under lake ice, obtained using an original method based on a set of two synchronized acoustic Doppler profilers to measure all six turbulent stress components.
G. B. Kirillin +2 more
wiley +1 more source
Numerical investigation of thermal performance in unsteady Casson hybrid nanofluid flow across rotating disks under variable Darcy resistance and Joule heating. [PDF]
Discov NanoYasmin H, Al-Essa LA, Noor S, Haq I.
europepmc +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Inertial forces and elastohydrodynamic interaction of spherical particles in wall-bounded sedimentation experiments at low Re P. [PDF]
Eur Phys J E Soft MatterNoichl I, Schönecker C.
europepmc +1 more source