Results 51 to 60 of about 6,372,670 (283)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Prefix Data Augmentation for Contrastive Learning of Unsupervised Sentence Embedding

open access: yesApplied Sciences
This paper presents prefix data augmentation (Prd) as an innovative method for enhancing sentence embedding learning through unsupervised contrastive learning.
Chunchun Wang, Shu Lv
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A comment on the training of unsupervised neural networks for learning phases

open access: yesResults in Physics, 2022
The impact on the performance of an unsupervised neural network (NN) for learning the phases of two-dimensional ferromagnetic Potts model, namely a deep learning autoencoder (AE), from using various training sets is investigated.
Yuan-Heng Tseng, Fu-Jiun Jiang
doaj   +1 more source

Unsupervised learning in noise [PDF]

open access: yesIEEE Transactions on Neural Networks, 1990
A new hybrid learning law, the differential competitive law, which uses the neuronal signal velocity as a local unsupervised reinforcement mechanism, is introduced, and its coding and stability behavior in feedforward and feedback networks is examined.
openaire   +2 more sources

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Deep Temporal Iterative Clustering for Satellite Image Time Series Land Cover Analysis

open access: yesRemote Sensing, 2022
The extensive amount of Satellite Image Time Series (SITS) data brings new opportunities and challenges for land cover analysis. Many supervised machine learning methods have been applied in SITS, but the labeled SITS samples are time- and effort ...
Wenqi Guo   +4 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Unsupervised Learning of Monocular Depth and Ego-Motion with Optical Flow Features and Multiple Constraints

open access: yesSensors, 2022
This paper proposes a novel unsupervised learning framework for depth recovery and camera ego-motion estimation from monocular video. The framework exploits the optical flow (OF) property to jointly train the depth and the ego-motion models.
Baigan Zhao   +3 more
doaj   +1 more source

PASTA‐ELN: Simplifying Research Data Management for Experimental Materials Science

open access: yesAdvanced Engineering Materials, EarlyView.
Research data management faces ongoing hurdles as many ELNs remain complex and restrictive. PASTA‐ELN offers an open‐source, cross‐platform solution that prioritizes simplicity, offline access, and user control. Its in tuitive folder structure, modular Python add‐ons, and open formats enable seamless documentation, FAIR data practices, and easy ...
S. Brinckmann, G. Winkens, R. Schwaiger
wiley   +1 more source

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