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Pathway Enrichment Analysis for Untargeted Metabolomics
Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology,and Health Informatics, 2017Metabolomics-based studies have provided critical insights across many applications and now offer researchers an opportunity to collect information about thousands of small molecules in-bulk through untargeted metabolomics. However, taking advantage of this new development requires accurate identification of metabolites and their biological ...
Vladimir Porokhin +2 more
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Machine Learning in Untargeted Metabolomics Experiments
2018Machine learning is a form of artificial intelligence (AI) that provides computers with the ability to learn generally without being explicitly programmed. Machine learning refers to the ability of computer programs to adapt when exposed to new data.
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Improving key steps in untargeted metabolomics
2022‘Non-targeted metabolomics’ zielt auf die umfassende Analyse kleiner Moleküle mit unter-schiedlichen chemischen Eigenschaften in Anbetracht ihrer Rolle in biologischen Systemen ab. Um mit dieser enormen Komplexität fertig zu werden, wurden hochmoderne analyti-sche Instrumente und bioinformatische Workflows entwickelt.
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Treelet transform for untargeted metabolomics data
2014In den letzten Jahrzehnten gab es zahlreiche Entwicklungen in der Metaboliterfassung in Gewebeproben – untargeted metabolomics [1] erfasst alle vorhandenen Verbindungen in einer biologischen Probe. Chromatographie und Massenspektrometrie ermöglichen eine präzisere Darstellung des menschlichen Metabolismus, welcher hunderte von Metaboliten und ihre ...
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Untargeted Metabolomics Revealed Metabolomic Profile in Patients with Primary Systemic Sclerosis
Applied Biochemistry and BiotechnologySystemic sclerosis (SSc) is a systemic autoimmune disease characterized by increased morbidity and mortality. The intestinal microbiome and serum metabolites had been implicated in SSc, but the connection between the gut microbiome and serum metabolites remains poorly understood.
Jinling, Tang, Pinglang, Ruan, Zhu, Wei
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Metabolomics in cancer research and emerging applications in clinical oncology
Ca-A Cancer Journal for Clinicians, 2021Daniel R Schmidt +2 more
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Mass spectrometry-based metabolomics in microbiome investigations
Nature Reviews Microbiology, 2021Anelize Bauermeister +2 more
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Enhancing untargeted metabolomics using metadata-based source annotation
Nature Biotechnology, 2022Michael J Meehan +2 more
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