Results 131 to 140 of about 82,838 (255)

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Determination and Pharmacokinetic of Peiminine in Beagle Dogs by UPLC-MS/MS. [PDF]

Int J Anal Chem
Cheng Q, Peng X, Li X, Jia X.
europepmc   +1 more source

Optimized SPE-UPLC-MS/MS Method for Sensitive Determination of Cereulide in Complex InfantFormula Matrices. [PDF]

Toxins (Basel)
Zhou Z, Wang Z, Mu C, Qi Y, Zhang J, Cui X, Fan S, Xiao J, Zhao R.   +8 more
europepmc   +1 more source

Profiling metabolites of Ficus natalensis hochst. fruit by UPLC-MS/MS and evaluation of anti-inflammatory activity. [PDF]

Sci Rep
Shawky EM, Hamdy R, Baky MH.
europepmc   +1 more source

Development of a Sensitive UPLC-MS/MS Method for the Simultaneous Quantification of Mycotoxins in Wheat Products and Human Urine. [PDF]

Toxins (Basel)
Gao B, Sun J, Xu Z, Li X, Ma J, Han X, Wang S.   +6 more
europepmc   +1 more source

Development of a UPLC-MS/MS method and its application for the pharmacokinetic analysis of regorafenib in rats. [PDF]

Sci Rep
Otto F, Propisnova V, Urjasz H, Lewandowski K, Sarnowski K, Szałek E, Karbownik A.   +6 more
europepmc   +1 more source

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

Animal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin, Jiantao Yang, Minglu Gao, Xiaozhao Tao, Xin Yang, Yanli Liu, Xiaojun Yang   +6 more
wiley   +1 more source

Comprehensive UPLC-MS/MS Profiling of Bioactive Phenolics and Their MYB Regulatory Networks in Wild and Cultivated Strawberries. [PDF]

Molecules
Rao MJ, Song K, He S, He S, Li Y, Zainuddin IM, Chen Y, Du X, Liu W, Shad MA, Tahira M, Duan X, Zheng B, Bao L, Yang S, Duan M.   +15 more
europepmc   +1 more source

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim, Amy Thachil, Kelly McMahon, Ross T. Tsuyuki, S. Rod Rassekh, Lesley G. Mitchell, Prasad Devarajan, Cherry Mammen, Bruce C. Carleton, Geoffrey D. E. Cuvelier, Victor A. Lewis, Colin J. D. Ross, Alexandra P. Zorzi, Sylvain Baruchel, Raveena Ramphal, Eric Bouffet, Mathieu Lemaire, Tom D. Blydt‐Hansen, Brad L. Urquhart, The Applying Biomarkers to Minimize Long‐Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Study Group, Tom Blydt‐Hansen, Bruce C. Carleton, Geoff D. E. Cuvelier, Sunil Desai, Prasad Devarajan, Conrad Fernandez, Adam Fleming, Paul Gibson, Caroline Laverdiere, Victor Lewis, Mary L. McBride, Bruno Michon, Shahrad Rod Rassekh, Colin J. D. Ross, Christine Sabapathy, Kirk R. Schultz, Michael Zappitelli, Alexandra Zorzi   +37 more
wiley   +1 more source

Comparison of an HPLC-UV system (LM1010) and UPLC-MS/MS for plasma voriconazole measurement in routine clinical practice. [PDF]

J Pharm Health Care Sci
Nakagawa J, Ueno K, Osanai K, Ishiyama M, Matsushita M, Morikawa S, Tomita H, Niioka T.   +7 more
europepmc   +1 more source