Results 151 to 160 of about 82,838 (255)

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

Biotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson, Jessica Willmott, Holly Corrigall, Daniela Lega, Joseph Stirling, Vithiya Vimalraj, Mitul Patel, Robyn Emmins   +7 more
wiley   +1 more source

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

Metabolomics Based on UPLC-MS/MS Revealed the Metabolic Differences Among Four Species of Rhododendrons in Linzhi, Xizang. [PDF]

Metabolites
Zhang Z, Kang S, Chen M, Sang M, Lv B, Pan Y, Chang Z.   +6 more
europepmc   +1 more source

Successive Azide and DNA Functionalization for Reversible and Controlled Association of Single‐Wall Carbon Nanotubes

Chemistry – A European Journal, EarlyView.
A newly synthesized bifunctional azide—diazonium linker allows robust one‐step introduction of azido groups to single‐wall carbon nanotubes. Versatility of the azido groups as reactive handles is demonstrated by further derivatization with 6‐carboxyfluorescein and oligonucleotides.
Razieh Moosavi, Tharun K. Kotammagari, Pia Damlin, Mikko Salomäki, Mika Lastusaari, Han Li, Tuomas Lönnberg   +6 more
wiley   +1 more source

UPLC-MS/MS Analytical Method for the Simultaneous Quantification of Diazepam, Nordazepam, and Oxazepam in Patients With Alcohol Dependence. [PDF]

Alpha Psychiatry
Li XL, Huang WT, Ni XJ, Lu HY, Huang SQ, Li YQ, Xie HS, Wen YG, Wang ZZ, Shang DW.   +9 more
europepmc   +1 more source

Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core

Chemistry – A European Journal, EarlyView.
RNA‐cleaving agents on a cubic octameric silsesquioxane core were synthesized and characterized. Several catalytic systems of these structures were screened using hexaribonucleotide models. The best systems were then further used to study their catalytic efficiency in cleaving a HER2 mRNA model sequence. The induced cleavage sites were also determined.
Hanni Haapsaari, Iris Tuomi, Pasi Virta
wiley   +1 more source

Measuring feather and plasma corticosterone in male broiler chickens: uplc-ms/ms methodology and feather growth dynamics. [PDF]

BMC Vet Res
Soster P, Carvalho CL, Buyse K, Cherlet M, Tuyttens F, Dedeurwaerder A, Verbeure W, Van Praet S, de Gussem M, Antonissen G.   +9 more
europepmc   +1 more source

Determination of Geniposide in Rat Plasma by UPLC-MS

Asian Journal of Chemistry, 2013
Yue Ding, Tong Zhang, Jian-Sheng Tao, Chun-Rong Guo, Min-Yi Jin, Guang Ji   +5 more
openaire   +1 more source

Understanding Consumption of Illicit Drugs and New Psychoactive Substances in Australia by Triangulating Drug Checking and Wastewater‐Based Epidemiology

Drug Testing and Analysis, EarlyView.
First Australian study combining wastewater‐based epidemiology and drug checking, demonstrating how complementary data sources enhance monitoring of illicit drugs and emerging psychoactive substances during high‐use periods. ABSTRACT Consumption of psychotropic drugs is a major economic and public health challenge in Australia.
Muhammad Usman, Malcolm McLeod, Dhayaalini Nadarajan, Joseph Clokey, Pritesh Prasad, Rory Verhagen, Benjamin Tscharke, Maurizio Quinto, Richard Bade   +8 more
wiley   +1 more source

A Systematic Study of the Hepatic-Intestinal First-Pass Effect and Excretion Pathways of Punicalagin Based on UPLC-MS/MS. [PDF]

Molecules
Chen Z, Chang Z, Yao P, Gao X.
europepmc   +1 more source