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Inhibitory effect of resveratrol on the pharmacokinetic of ibrutinib by UPLC–MS/MS
Drug Development and Industrial Pharmacy, 2019To investigate the impact of resveratrol on the metabolism of ibrutinib in vitro and in vivo.In vitro, rat liver microsomes (RLM) and human liver microsomes (HLM) were used to study. In vivo, 18 male SD rats were randomly divided into three groups (n = 6): ibrutinib and the multiple dose of 100 mg/kg resveratrol for consecutive 7 days (Group A ...
Jian, Wen +6 more
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[UPLC-MS / MS for the pharmacokinetics of icariin in rats].
Wei sheng yan jiu = Journal of hygiene research, 2018To establish an ultra-performance liquid chromatographytandem mass spectrometry( UPLC-MS / MS) method for the quantification of icariin( ICA), and investigate pharmacokinetics of ICA in rats following multiple oral administration.ICA and an internal standard coumestrol( CMT) were extracted from rat plasma using ethyl acetate and separated on a BEH C18(
Shuangqing, Zhang +2 more
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History and Introduction of UPLC/MS
2014Mu Naushad, Mohammad Khan, Zeid Alothman
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Structure identification of the oligosaccharides by UPLC-MS/MS
Food Hydrocolloids, 2023Qiuxia Yang +3 more
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Determination of degradation impurities in nepafenac by UPLC-MS
2015The degradation studies were performed on Nepafenac active pharmaceutical ingredient in order to qualify potential degradation impurities. Degradation products of Nepafenac formed under different forced conditions have been identified using LC-PDA and LC-MS techniques.
Babić, Sandra, Meštrović, Ernest
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Multiplex Measurement of Serum Folate Vitamers by UPLC-MS/MS
2016The implementation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to measure six folate vitamers in serum samples allows a more individual and accurate measurement than the commonly used immunoassays. In the described method, serum samples undergo solid phase extraction followed by liquid chromatography coupled with electrospray ...
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Impact of UPLC-MS in Food and Drug/Metabolite Analysis
Current Pharmaceutical Analysis, 2021Kritika Verma +2 more
exaly
Determination of multiple mycotoxins in feedstuffs by combined use of UPLC–MS/MS and UPLC–QTOF–MS
Food Chemistry, 2018Eva Maria Mateo +2 more
exaly