Results 101 to 110 of about 156,468 (326)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

New bounds for the minimum eigenvalue of 𝓜-tensors

Open Mathematics, 2017
A new lower bound and a new upper bound for the minimum eigenvalue of an 𝓜-tensor are obtained. It is proved that the new lower and upper bounds improve the corresponding bounds provided by He and Huang (J. Inequal.
Zhao Jianxing, Sang Caili
doaj   +1 more source

On Upper and Lower Bounds on the Length of Alternating Towers [PDF]

, 2014
A tower between two regular languages is a sequence of strings such that all strings on odd positions belong to one of the languages, all strings on even positions belong to the other language, and each string can be embedded into the next string in the sequence.
Stepan Holub, Galina Jirásková, Tomás Masopust   +2 more
openaire   +5 more sources

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Upper and Lower Bounds on the Smoothed Complexity of the Simplex Method [PDF]

TheoretiCS
The simplex method for linear programming is known to be highly efficient in practice, and understanding its performance from a theoretical perspective is an active research topic. The framework of smoothed analysis, first introduced by Spielman and Teng
Sophie Huiberts, Yin Tat Lee, Xinzhi Zhang   +2 more
doaj   +1 more source

Exact Upper and Lower Bounds on the Misclassification Probability [PDF]

IEEE Transactions on Information Theory, 2019
Exact lower and upper bounds on the best possible misclassification probability for a finite number of classes are obtained in terms of the total variation norms of the differences between the sub-distributions over the classes. These bounds are compared with the exact bounds in terms of the conditional entropy obtained by Feder and Merhav.
openaire   +3 more sources

Ky Fan Inequality and Bounds for Differences of Means [PDF]

, 2002
We prove an equivalent relation between Ky Fan-typed inequalities and certain bounds for the differences of means. We also generalize a result of H. Alzer, S.
Peng Gao, Gao, Peng, Peng Gao
core   +2 more sources

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source