Results 81 to 90 of about 156,468 (326)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Upper and lower bounds of integral operator defined by the fractional hypergeometric function

open access: yesOpen Mathematics, 2015
In this article, we impose some studies with applications for generalized integral operators for normalized holomorphic functions. By using the further extension of the extended Gauss hypergeometric functions, new subclasses of analytic functions ...
Ibrahim Rabha W.   +2 more
doaj   +1 more source

Bounds for the Z-eigenpair of general nonnegative tensors

open access: yesOpen Mathematics, 2016
In this paper, we consider the Z-eigenpair of a tensor. A lower bound and an upper bound for the Z-spectral radius of a weakly symmetric nonnegative irreducible tensor are presented.
Liu Qilong, Li Yaotang
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Upper and lower bounds for a reactive-diffuse system with Arrhenius kinetics

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2006
Comparison arguments are used to study a problem in combustion theory consisting of a nonlinear parabolic equation together with initial and boundary conditions. Upper and lower bounds for the problem are constructed.
Mohammed Al-Refai, Qutaibeh Katatbeh
doaj   +1 more source

Upper and lower bounds for sums of random variables. [PDF]

open access: yes
In this contribution, the upper bounds for sums of dependent random variables X1 + X2 + … + X n derived by using comonotonicity are sharpened for the case when there exists a random variable Z such that the distribution functions of the Xi, given Z = z ...
Kaas, R, Goovaerts, Marc, Dhaene, Jan
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

On a unified integral operator for φ-convex functions

open access: yesAdvances in Difference Equations, 2020
Integral operators have a very vital role in diverse fields of science and engineering. In this paper, we use φ-convex functions for unified integral operators to obtain their upper bounds and upper and lower bounds for symmetric φ-convex functions in ...
Young Chel Kwun   +4 more
doaj   +1 more source

On Bounds for Concave Distortion Risk Measures for Sums of Risks [PDF]

open access: yes
In this paper we consider the problem of studying the gap between bounds of risk measures for sums of non-independent random variables. Owing to the choice of the context where to set the problem, namely that of distortion risk measures, we first deduce ...
Antonella Campana, Paola Ferretti
core  

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