Results 81 to 90 of about 60,982 (263)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Exact Upper and Lower Bounds on the Misclassification Probability [PDF]
IEEE Transactions on Information Theory, 2019 Exact lower and upper bounds on the best possible misclassification probability for a finite number of classes are obtained in terms of the total variation norms of the differences between the sub-distributions over the classes. These bounds are compared with the exact bounds in terms of the conditional entropy obtained by Feder and Merhav.
openaire +2 more sources
On Upper and Lower Bounds on the Length of Alternating Towers [PDF]
, 2014 A tower between two regular languages is a sequence of strings such that all strings on odd positions belong to one of the languages, all strings on even positions belong to the other language, and each string can be embedded into the next string in the sequence.
Stepan Holub +2 more
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FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Upper and Lower Bounds on the Smoothed Complexity of the Simplex Method [PDF]
TheoretiCSThe simplex method for linear programming is known to be highly efficient in practice, and understanding its performance from a theoretical perspective is an active research topic. The framework of smoothed analysis, first introduced by Spielman and Teng
Sophie Huiberts +2 more
doaj +1 more source
New Upper and Lower Bounds for Ramsey Numbers
European Journal of Combinatorics, 2001 The Ramsey number \(R(G_1, G_2)\) is the smallest integer \(p\) such that for any graph \(G\) on \(p\) vertices either \(G\) contains the graph \(G_1\) or the complement \(\overline G\) of \(G\) contains the graph \(G_2\). The paper presents some new upper and lower bound formulas for \(R(G_1,G_2)\) and \(R(K_m, K_n)\).
Yi Ru Huang, Jian Sheng Yang
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FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Lower and Upper Bounds On Irregularities of Distribution
, 2020 See the abstract in the attached pdf.
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FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source