Results 61 to 70 of about 60,982 (263)

An upper and lower bound for clock synchronization

Information and Control, 1984
Summary: The problem of synchronizing clocks of processes in a fully connected network is considered. It is proved that, even if the clocks all run at the same rate as real time and there are no failures, an uncertainty of \(\epsilon\) in the message delivery time makes it impossible to synchronize the clocks of n processes any more closely than ...
Jennifer Lundelius, Nancy A. Lynch
openaire   +2 more sources

Upper and Lower Bounds on Black-Box Steganography [PDF]

Journal of Cryptology, 2005
We study the limitations of steganography when the sender is not using any properties of the underlying channel beyond its entropy and the ability to sample from it. On the negative side, we show that the number of samples the sender must obtain from the channel is exponential in the rate of the stegosystem.
Nenad Dedic, Gene Itkis, Leonid Reyzin, Scott Russell   +3 more
openaire   +5 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Upper and Lower Bounds for Ranks of the Matrix Expression X-XAX

Abstract and Applied Analysis, 2013
We consider the question of how to take X such that the nonlinear matrix expression X-XAX attains its maximal and minimal possible ranks.
Zhiping Xiong
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Upper and lower bounds of integral operator defined by the fractional hypergeometric function

Open Mathematics, 2015
In this article, we impose some studies with applications for generalized integral operators for normalized holomorphic functions. By using the further extension of the extended Gauss hypergeometric functions, new subclasses of analytic functions ...
Ibrahim Rabha W., Ahmad Muhammad Zaini, Al-Janaby Hiba F.   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Upper and lower bounds for a reactive-diffuse system with Arrhenius kinetics

International Journal of Mathematics and Mathematical Sciences, 2006
Comparison arguments are used to study a problem in combustion theory consisting of a nonlinear parabolic equation together with initial and boundary conditions. Upper and lower bounds for the problem are constructed.
Mohammed Al-Refai, Qutaibeh Katatbeh
doaj   +1 more source

On a unified integral operator for φ-convex functions

Advances in Difference Equations, 2020
Integral operators have a very vital role in diverse fields of science and engineering. In this paper, we use φ-convex functions for unified integral operators to obtain their upper bounds and upper and lower bounds for symmetric φ-convex functions in ...
Young Chel Kwun, Moquddsa Zahra, Ghulam Farid, Saira Zainab, Shin Min Kang   +4 more
doaj   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source