Results 51 to 60 of about 60,982 (263)

An Upper Bound on the Error Induced by Saddlepoint Approximations—Applications to Information Theory

open access: yesEntropy, 2020
This paper introduces an upper bound on the absolute difference between: ( a ) the cumulative distribution function (CDF) of the sum of a finite number of independent and identically distributed random variables with finite absolute third moment;
Dadja Anade   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Young's integral inequality with upper and lower bounds

open access: yesElectronic Journal of Differential Equations, 2011
Young's integral inequality is reformulated with upper and lower bounds for the remainder. The new inequalities improve Young's integral inequality on all time scales, such that the case where equality holds becomes particularly transparent in this ...
Douglas R. Anderson   +2 more
doaj  

Upper and lower bounds for competitive group testing

open access: yesDiscrete Applied Mathematics, 2023
We consider competitive algorithms for adaptive group testing problems. In the first part of the paper, we develop an algorithm with competitive constant c < 1.452 thus improving the up to now best known algorithms with constants 1.5+epsilon from 2003.
Robert Scheidweiler, Eberhard Triesch
openaire   +3 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Independence number in graphs and its upper bounds [PDF]

open access: yesJournal of Mahani Mathematical Research
‎In this paper, we use the double counting method to find some upper bounds for the independence number of a simple graph in terms of its order, size and  maximum degree.   Moreover,  we determine extremal graphs attaining equality in upper bounds.
Farzad Shaveisi
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Bounds for the Z-eigenpair of general nonnegative tensors

open access: yesOpen Mathematics, 2016
In this paper, we consider the Z-eigenpair of a tensor. A lower bound and an upper bound for the Z-spectral radius of a weakly symmetric nonnegative irreducible tensor are presented.
Liu Qilong, Li Yaotang
doaj   +1 more source

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