Results 71 to 80 of about 60,982 (263)
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Properties of virtual MIMO signal and interference in cooperation cognitive networks
Tongxin xuebao, 2012 A virtual MIMO scheme based on cooperation of the prim and secondary users was proposed in the wireless cognitive networks.The tight upper and lower bounds about the complimentary cumulative distribution function of the virtual MIMO signal and ...
Xu BAO, Tie-cheng SONG, Lian-feng SHEN
doaj +2 more sources
New bounds for the minimum eigenvalue of 𝓜-tensors
Open Mathematics, 2017 A new lower bound and a new upper bound for the minimum eigenvalue of an 𝓜-tensor are obtained. It is proved that the new lower and upper bounds improve the corresponding bounds provided by He and Huang (J. Inequal.
Zhao Jianxing, Sang Caili
doaj +1 more source
A Novel Approach for Searching the Upper/Lower Bounds of Uncertainty Parameters in Microgrids
Energies, 2018 In this study, a novel method based on μ analysis is presented to search for the upper/lower bounds of uncertainty parameters in microgrids (MGs).
Xiaojun Ding +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
New Lower and Upper Bounds for Representing Sequences [PDF]
, 2012 Sequence representations supporting queries access, select and rank are at the core of many data structures. There is a considerable gap between different upper bounds, and the few lower bounds, known for such representations, and how they interact with the space used.
Belazzougui, Djamal, Navarro, Gonzalo
openaire +4 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source