Results 221 to 230 of about 298,897 (298)

Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons

Advanced Science, EarlyView.
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen‐xia Tian, Longlong Si   +14 more
wiley   +1 more source

Health care costs of major upper-extremity amputations in Ontario: a retrospective matched-cohort analysis with considerations for transplantation. [PDF]

Can J Surg
Duru Ç, Hadzimustafic N, Haykal S.
europepmc   +1 more source

Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing

Advanced Science, EarlyView.
This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang, Mingjie Kuang, Jiacheng Shi, Ruiyan Li, Yuhan Zhang, Xinting Liu, Runtan Li, Yong Kang, Bin Yao, Shuquan Zhang, Xiaoyuan Ji   +10 more
wiley   +1 more source

Association between quantitative cervical cord compression metrics and upper extremity impairments in degenerative cervical myelopathy: a cross-sectional study. [PDF]

Front Neurol
Wang Z, Lin C, Si X, Wu Z.
europepmc   +1 more source

Distal humerus allograft and double internal joint stabilizer reconstruction for chronic lateral humerus condyle nonunion with posterolateral instability: a case report

JSES Reviews, Reports, and Techniques
Diego Gonzalez-Morgado, MD, PhD, Kevin A. Hao, MD, Barret Halgas, MD, Farbod Malek, MD, Spencer Falcon, MD, Jordan Carter, MD, Jorge L. Orbay, MD, Ramesh C. Srinivasan, MD   +7 more
doaj   +1 more source

Capture and Culture of Circulating Tumor Cells Using a Biodegradable 3D Scaffold for Patient‐Derived Xenograft Construction

Advanced Science, EarlyView.
A self‐supporting, biocompatible, and biodegradable 3D cellulose scaffold has been developed for efficient isolation and in situ expansion of circulating tumor cells (CTCs) from patient blood. Subsequently, the 3D cellulose scaffold with cultured CTCs is directly implanted into immunodeficient mice for constructing patient CTC‐derived xenograft (CDX ...
Yi‐Ke Wang, Ming Wang, Min Liu, Yi‐Jing Chen, Li‐Li Xu, Jin‐Ping Zhou, Fu‐Bing Wang, Shi‐Bo Cheng, Min Xie, Wei‐Hua Huang   +9 more
wiley   +1 more source

The implementation of artificial intelligence in upper extremity surgery: a systematic review. [PDF]

Front Artif Intell
Parry D, Henderson B, Gaschen P, Ghanem D, Hernandez E, Idicula A, Hanna T, MacKay B.   +7 more
europepmc   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Effectiveness of myoelectric wearable orthoses for upper extremity functional recovery in spinal cord injury- a pilot study. [PDF]

J Neuroeng Rehabil
Androwis GJ, Engler A, Craven C, Eng J, Gaite A, Rana S, AlRabadi S, Ramirez J, Salloum R, Alvarez C, Wassef M, Huzien M, Snider B, Kirshblum S, Yue GH.   +14 more
europepmc   +1 more source