Results 71 to 80 of about 141,219 (353)

Phospholipid Remodeling and Tri‐Layer Membrane Reconstruction Mediate Cognitive Effects of Humanized Milk Fat Globules in Neonatal Rats

Advanced Science, EarlyView.
Humanized milk fat globules (MFG) mimic the native composition and structure of human milk, achieved through remodeling of milk fat globule membrane phospholipid composition and reconstruction of the tri‐layer membrane structure. These humanized MFG exhibit improved structural stability and digestibility, and enhance neurodevelopment in formula‐fed rat
Shaolei Wang, Fengzhi Qiao, Jian He, Jianxin Fu, Tongjie Liu, Huaxi Yi, Qinghai Sheng, Lanwei Zhang, Kai Lin   +8 more
wiley   +1 more source

Reducing gastrointestinal tract bleeding in family practice

South African Family Practice, 2008
Upper gastrointestinal bleeding occurs commonly. Fortunately, severe life-threatening bleeding is less common, but can be catastrophic, particularly in the elderly patient with co-morbidity such as cardiac or respiratory disease.
Herbie R. Schneider
doaj   +1 more source

7‐Ketodeoxycholic Acid Promotes Colonic Mucosal Healing by Inducing Calcium Release from Endoplasmic Reticulum via the TGR5‐IP3R Pathway

Advanced Science, EarlyView.
7‐KDCA functions by driving intestinal epithelial cell migration through induction of calcium release from the endoplasmic reticulum. The findings emphasize a previously unrecognized property of 7‐KDCA in regulating cell migration, a required process for effective epithelial restitution and repair that is particularly critical for patients with UC to ...
Jing Zhang, Feng Jiang, Wenxin Xia, Yilei Guo, Yanrong Zhu, Mianjiang Zhao, Lingzi Xiao, Zhifeng Wei, Yufeng Xia, Yue Dai   +9 more
wiley   +1 more source

Access and non–access site bleeding after percutaneous coronary intervention and risk of subsequent mortality and major adverse cardiovascular events:Systematic review and meta-analysis [PDF]

, 2015
Background: The prognostic impact of site-specific major bleeding complications after percutaneous coronary intervention (PCI) has yielded conflicting data.
Buchan, Iain, de Belder, Mark A., Khan, Muhammad A., Kinnaird, Tim, Kwok, Chun Shing, Loke, Yoon K., Ludman, Peter F., Mamas, Mamas A, Nolan, James, Rao, Sunil V., Sperrin, Matt   +10 more
core   +1 more source

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

Advanced Science, EarlyView.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi, Yang‐Xun Zhang, Jun‐Yi Chen, Sai Ma, Wei‐Xuan Xue, Wei Li, Qian‐Xiao Li, Bo Song, Ya‐Ting Li, Hong‐Yu Ma, Shu‐Tao Xie, Hong‐Zhao Li, Di‐Jun Chen, Qi‐Peng Zhang, Hui‐Jie Ma, Jian‐Jun Wang, Lei Yu, Xiao‐Yang Zhang, Jing‐Ning Zhu   +18 more
wiley   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

Gastrointestinal Bleeding in COVID-19 Patients: A Systematic Review with Meta-Analysis

Canadian Journal of Gastroenterology and Hepatology, 2021
The novel coronavirus disease 2019 (COVID-19) has been reported to affect the gastrointestinal system with a variety of symptoms, including bleeding. The prevalence of bleeding in these patients remains unclear.
Giovanni Marasco, Marcello Maida, Gaetano Cristian Morreale, Massimo Licata, Matteo Renzulli, Cesare Cremon, Vincenzo Stanghellini, Giovanni Barbara   +7 more
doaj   +1 more source

Coil-Assisted Retrograde Transvenous Obliteration (CARTO) for the Treatment of Portal Hypertensive Variceal Bleeding: Preliminary Results. [PDF]

, 2014
ObjectivesTo describe the technical feasibility, safety, and clinical outcomes of coil-assisted retrograde transvenous obliteration (CARTO) in treating portal hypertensive non-esophageal variceal hemorrhage.MethodsFrom October 2012 to December 2013, 20 ...
Busuttil, Ronald, Durazo, Francisco, Goldstein, Leonard, Gomes, Antoinette S, Han, Steven-Huy, Kee, Stephen T, Lee, Edward W, Loh, Christopher T, McWilliams, Justin, Moriarty, John, Saab, Sammy, Tafti, Bashir A   +11 more
core   +2 more sources

A Single‐Component Adhesive Sponge Based on Blood‐Triggered and Autopenetrative Adhesion for Robust Vascular Closure

Advanced Science, EarlyView.
This study presents MonoSeal, a single‐component adhesive sponge powered by the novel Autopenetrative Adhesion (APA) mechanism. Unlike traditional adhesives, which require external stimuli, APA enables strong tissue adhesion under dynamic, high‐pressure bleeding conditions. MonoSeal's ability to autonomously seal large‐size arterial defects underscores
Rong Wang, Weishi Zheng, Yuxuan Huang, Rui Zhang, Yi Zhang, Jingying Yan, Yuqing Gu, Jingyun Xi, Tun Yuan, Hua Su, Xianzhu Zhang, Xiaozhao Wang, Shaohui Xiong, Zhenfeng Cheng, Hongwei Ouyang, Yi Hong   +15 more
wiley   +1 more source

Causes and outcomes of upper gastrointestinal bleeding in referral hospitals in Rwanda: a prospective study

Rwanda Medical Journal
INTRODUCTION: Upper gastrointestinal (GI) bleeding is a common emergency that results in significant morbidity and mortality. In Rwanda, data on causes and outcomes are lacking.
D. Nyampinga, E. Rutaganda, F. Shikama, Z. Ingabire, S. Mukanumviye, S. Turikumwe, H. Aberra, B. Redae, B. Seminega, V. Dusabejambo, D. J. van Leeuwen   +10 more
doaj   +1 more source