Results 171 to 180 of about 386,287 (343)
JPGN Reports, EarlyView.Abstract The diagnosis of autoimmune hepatitis (AIH) is supported by the presence of elevated transaminases, hypergammaglobulinemia, liver biopsy consistent with AIH, and the presence of AIH autoantibodies. In this case presentation, we highlight the challenges associated with diagnosing AIH in a patient with inflammatory bowel disease (IBD) who ...
Benjamin J. Malamet +5 more
wiley +1 more source
Case series: Joubert syndrome and eosinophilic esophagitis
JPGN Reports, EarlyView.Abstract Joubert syndrome (JS) is a rare genetic disorder characterized by developmental abnormalities, particularly in the brainstem and cerebellar vermis, alongside multisystem manifestations such as kidney and liver anomalies, polydactyly, cleft lip or palate, and tongue defects.
Jonathon Schening +5 more
wiley +1 more source
When protein losing enteropathy persists: A case series of viral and lymphatic‐associated etiologies
JPGN Reports, EarlyView.Abstract Protein‐losing enteropathy (PLE) is a rare condition that is characterized by loss of plasma protein in the intestines leading to hypoproteinemia with subsequent peripheral edema and possibly anasarca. The pathophysiology of PLE varies depending on the etiology and involves either intestinal mucosal injury or lymphatic system alterations ...
Natalie Jennings +7 more
wiley +1 more source
Journal of Surgical Oncology, EarlyView.ABSTRACT Background and Objective Palliative surgery in oncology aims to relieve symptoms, improve quality of life, and respect patient autonomy in advanced cancer. This study aimed to develop evidence‐based recommendations for safely indicating and performing palliative surgeries in Brazil, considering clinical, ethical, and multidisciplinary aspects.
Audrey Cabral Ferreira de Oliveira +15 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Baricitinib is a selective Janus kinase (JAK)1/JAK2 inhibitor approved in more than 70 countries for the treatment of moderate‐to‐severe atopic dermatitis (AD) in adults, and in over 30 countries for adolescents and children from age 2 years with moderate‐to‐severe AD, who are candidates for systemic therapy.
Antonio Costanzo +11 more
wiley +1 more source
Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino +3 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Biologics and Janus kinase inhibitors (JAKi) are two advanced systemic treatment options for patients with atopic dermatitis (AD). The decision to initiate one of these therapies is complex and may be driven by many factors.
Eric L. Simpson +12 more
wiley +1 more source
Gomal Journal of Medical Sciences, 2004 Lower respiratory tract infections are a common problem in our society. In recurrent lower respiratory tract infections the cause may be either general impairment of immune mechanism, abnormalities of mucus or abnormalities of cilia.
Ihsan-ullah Mahsud, Shahab ud Din
doaj
Evaluation of Management Strategies for Viral Upper Respiratory Tract Infections Among Pediatricians in Türkiye. [PDF]
Infect Drug ResistYildiz I +5 more
europepmc +1 more source