Results 61 to 70 of about 2,357,761 (180)

Integrated Analysis of HER2 Expression and ERBB2 Alterations in Bladder Cancer

Cancer Science, EarlyView.
Integrated analysis of 445 bladder cancers showed that HER2 membrane expression and ERBB2 amplification are distinct features. HER2 expression overlapped with NECTIN4 expression, whereas ERBB2 amplification was enriched in the LumU subtype and associated with poor prognosis.
Kensuke Hirosuna, Kazuki Nishimura, Moritoshi Sakamoto, Satoshi Tokushige, Keita Nakamori, Tomohisa Matsunaga, Yuki Yoshikawa, Takeshi Tsutsumi, Ryoichi Maenosono, Takuya Tsujino, Masahiko Ajiro, Haruhito Azuma, Akihide Yoshimi, Kazumasa Komura   +13 more
wiley   +1 more source

Concurrent Preoperative Presence of Hydronephrosis and Flank Pain Independently Predicts Worse Outcome of Upper Tract Urothelial Carcinoma. [PDF]

PLoS ONE, 2015
To investigate the impact of preoperative hydronephrosis and flank pain on prognosis of patients with upper tract urothelial carcinoma.In total, 472 patients with upper tract urothelial carcinoma managed by radical nephroureterectomy were included from ...
Hsin-Chih Yeh, Hau-Chern Jan, Wen-Jeng Wu, Ching-Chia Li, Wei-Ming Li, Hung-Lung Ke, Shu-Pin Huang, Chia-Chu Liu, Yung-Chin Lee, Sheau-Fang Yang, Peir-In Liang, Chun-Nung Huang   +11 more
doaj   +1 more source

Refining risk stratification after indeterminate urinary cytology: Evidence from Bladder EpiCheck

Cancer Cytopathology, Volume 134, Issue 10, October 2026.
Abstract Background This study aimed to evaluate Bladder EpiCheck (BE) performance in detecting urothelial carcinoma (UC) and HG (high‐grade) events in patients with indeterminate cytology and negative cystoscopy. Methods This prospective study included 63 patients who presented with indeterminate urinary cytology and negative cystoscopy between ...
Claudia Mercader, Mercedes Ingelmo‐Torres, Fiorella L. Roldán, Marcel Figueras, Eric Villalba, Pilar Galve, Ignacio Asiaín, Meritxell Costa, Antoni Vilaseca, Josep Oriola, Agustín Franco, Antonio Alcaraz, Lourdes Mengual   +12 more
wiley   +1 more source

Atypical presentations of UTUC: a case report of three patients

Frontiers in Oncology
BackgroundUpper tract urothelial carcinoma (UTUC) is a rare clinical condition primarily characterized by symptoms such as gross or microscopic hematuria, flank pain, and renal colic.
Linfa Guo, Xiaojie Bai, Kuerban Tuoheti, Xiaolong Wang, Tongzu Liu, Tongzu Liu, Tongzu Liu   +6 more
doaj   +1 more source

Diagnostic Role of F-18 Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography in Restaging of Upper Urinary Tract Urothelial Carcinoma

, 2017
Objective: To retrospectively evaluate contribution of F-18 fluorodeoxyglucose positron-emission tomography/computed tomography (18FDG-PET/CT) to re-staging of upper urinary tract urothelial carcinoma (UTUC). Materials and Methods: This study included a
Hakan Öztürk
core   +1 more source

Fibromyxoid Nephrogenic Adenoma Mimicking Renal Cell Carcinoma: A Diagnostic Pitfall in Fine‐Needle Aspiration Cytology

Diagnostic Cytopathology, Volume 54, Issue 10, Page E236-E239, October 2026.
ABSTRACT Nephrogenic adenoma (NA) is a benign lesion of the genitourinary tract that may mimic malignancy both clinically and histologically. The fibromyxoid variant (FMNA), characterized by spindled cells in myxoid stroma, presents additional diagnostic challenges due to its rarity and overlapping features with renal cell carcinoma (RCC).
Jodi Gedallovich, Adebola Adeniyi, Ankur R. Sangoi, Xiaohua Qian, Kelly Ernst   +4 more
wiley   +1 more source

Tumor heterogeneity evaluated by computed tomography detects muscle-invasive upper tract urothelial carcinoma that is associated with inflammatory tumor microenvironment

Scientific Reports, 2021
To detect muscle-invasive upper tract urothelial carcinoma, we evaluated the internal texture of the tumor using texture analysis of computed tomography images in 86 cases of upper tract urothelial carcinoma.
Keisuke Goto, Yukiko Honda, Kenichiro Ikeda, Kenshiro Takemoto, Toru Higaki, Tetsutaro Hayashi, Kohei Kobatake, Yuko Nakamura, Yohei Sekino, Shogo Inoue, Kazuo Awai, Wataru Yasui, Jun Teishima   +12 more
doaj   +1 more source

A Novel Technique for the Distal Ureter and Bladder Cuff During Nephroureterectomy: Thulium Laser Resection

Trends in Urology &Men's Health, Volume 17, Issue 5, October 2026.
ABSTRACT The aim of this study was to evaluate the safety and feasibility of a novel technique involving the use of the two‐micron thulium fibre laser (Tm‐laser) to perform bladder cuff excision (BCE) during radical nephroureterectomy (RNU). We conducted a retrospective review of all patients undergoing RNU with BCE for upper tract urothelial carcinoma
Shravankrishna Ananthapadmanabhan, Jeremy Saad, Hong Soh, Darius Ashrafi, Hodo Haxhimolla   +4 more
wiley   +1 more source

Brain metastasis from renal urothelial carcinoma successfully treated by metastasectomy

Tzu Chi Medical Journal, 2018
Upper tract urothelial cancer (UTUC) arises from the urothelial lining of the urinary tract. UTUC spreads in several different ways including direct invasion, lymphatic spread, and hematogeneous metastases.
Wen-Kuei Fang, Yeong-Chin Jou, Yuan-Chang Dai, Pi-Chan Ko, Ya-Fang Huang   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, Volume 20, Issue 9, Page 2296-2322, September 2026.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source