Results 81 to 90 of about 2,357,761 (180)
An Audit of Nephroureterectomy for Upper Tract Urothelial Carcinoma
, 2011 Background: The boundary of nephroureterctomy has been revisited and lymph node dissection has been recommended recently. We investigated the role of synchronous ipsilateral adrenalectomy in treating patients with upper tract urothelial carcinoma ...
黃昭淵;鍾旭東;王碩盟;廖俊厚;賴明坤;黃國皓;蒲永孝;闕士傑;余宏政 +1 more
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IJU Case Reports, Volume 9, Issue 5, September 2026.ABSTRACT Introduction Pyelonephritis with contralateral vesicoureteral reflux (VUR) after robot‐assisted radical nephroureterectomy (RANU) in a solitary kidney has rarely been reported. Case Presentation A 73‐year‐old woman with preoperative lower urinary tract symptoms (LUTS; IPSS 15, OABSS 7) underwent right RANU for urothelial carcinoma of the renal
Shuhei Kusano +8 more
wiley +1 more source
Targeted sequencing of upper tract urothelial carcinoma.
, 2014 309 Background: Regardless of the anatomic location (renal pelvis or ureter (upper tract), bladder or urethra) urothelial carcinoma is considered a single entity. Outcomes differ depending on site of initial diagnosis.
A. Ari Hakimi +16 more
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A Case of Robot‐Assisted Radical Cystectomy for a Third Kidney Transplant Recipient
IJU Case Reports, Volume 9, Issue 5, September 2026.ABSTRACT Introduction Although robot‐assisted surgery is widely used, there are few reports of robot‐assisted radical cystectomy in kidney transplant recipients. We report our experience with robot‐assisted radical cystectomy in a patient who had undergone three kidney transplants.
Fumito Yamabe +5 more
wiley +1 more source
MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen +3 more
wiley +1 more source
MedComm – Oncology, Volume 5, Issue 3, September 2026.The up‐to‐date clinical progress of immune checkpoint inhibitor (ICI) therapy in solid tumors, specifically the combinational regimens between ICIs and other treatment strategies, the mechanisms underlying primary and acquired resistance, and mechanism‐matched strategies to improve clinical outcomes are synthesized in this review.
Qiongyu Zhang, Zhi Qin, Caijuan Guo
wiley +1 more source
BJU International, Volume 138, Issue 3, Page 491-500, September 2026.Objectives To evaluate whether longitudinal tumour‐informed circulating tumour DNA (ctDNA) testing identifies patients at increased risk of upstaging and recurrence in high‐risk non‐muscle‐invasive bladder cancer (NMIBC). Patients and Methods A cohort of 52 patients with high‐risk NMIBC underwent serial plasma ctDNA testing using a personalised tumour ...
Can Aydogdu +17 more
wiley +1 more source
A case series: Four cases of urothelial carcinoma with sarcomatoid differentiation
Frontiers in OncologyUrothelial carcinoma with sarcomatoid differentiation (UCSD) is a rare and highly aggressive variant of urothelial carcinoma associated with poor prognosis. UCSD originating in the upper urinary tract is extremely uncommon, and its variable morphological
Haosong Ma +4 more
doaj +1 more source
K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder [PDF]
, 2011 The human fibroblast growth factor receptor 3 (FGFR3) gene is frequently mutated in superficial urothelial cell carcinoma (UCC). To test the functional significance of FGFR3 activating mutations as a ‘driver’ of UCC, we targeted the expression of mutated
Taketo, M.M. +17 more
core +1 more source
Cancer Science, Volume 117, Issue 9, Page 2366-2378, September 2026.UBE2C upregulates cellular CD147 and enhances its release into the tumor microenvironment both as soluble CD147 (sCD147) and packaged within tumor‐derived exosomes. These CD147‐bearing signals induce T‐cell exhaustion, marked by elevated CTLA‐4 expression and reduced secretion of effector cytokines (IFN‐γ, TNF‐α, TGF‐β), ultimately diminishing CD8+ T ...
Xuwei Hong +7 more
wiley +1 more source