Results 91 to 100 of about 20,944 (300)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
PRASA OKRESU POWSTANIA WARSZAWSKIEGO. „BIULETYN INFORMACYJNY” I JEGO STRUKTURA GATUNKOWA
Civitas et Lex, 2018 The presented paper concerns press in the period of the Warsaw Uprising, especially “Biuletyn Informacyjny”. Polish underground editing movement was the greatest amongst European countries covered by the World War II.
Wioleta Wróbel
doaj +1 more source
Historical sociology and the Arab Uprising [PDF]
, 2014 Historical sociology's perspectives—co-constitution of the international and domestic, path-dependency, variegated regime types—help illuminate the state formation paths leading to the Arab Uprising.
Hinnebusch, Raymond
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Artivistic interventions as humorous re-appropriations
The European Journal of Humour Research, 2015 The article reflects on the synergic interaction of artistic creativity and activist engagement through a humorous approach of some contemporary civilian protest actions in Slovenia.
Aldo Milohnic
doaj
PlaNext, 2015 Brazil experienced, in June of 2013, the largest popular demonstrations in its recent history —an event that has been called the June Journeys. In this paper, we briefly address briefly the processes of spatial diffusion and dispersion observed during ...
Rafael Gonçalves de Almeida +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source