Results 71 to 80 of about 20,944 (300)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A Surprising Uprising [PDF]

, 1972
Mitch Taylor supports actress in a chariot during production of "A Surprising Uprising" performed by the Dominguez ...

core   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Uprising (Aufruhr) [PDF]

, 1950
Medium: etchingnot signed, not dated."Uprising (Aufruhr)" [2010.0003.000.000], Kollwitz, KätheArtist and Role: Kollwitz, Käthe,Extent: imageExtent: plateExtent ...
Kollwitz, Käthe
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Warsaw Uprising of 1944 [PDF]

The Warsaw Uprising of 1944 was a major World War II operation by the Polish resistance Home Army (Armia Krajowa) to liberate Warsaw from Nazi German occupation.
Gusciora, Vanessa K
core   +3 more sources

Wladimir Krzyzanowski, 123 Polish Hero of the Civil War in the USA

Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2014
The article is dedicated to the young Polish revolutionist Wladimir Krzyzanowski who emigrated from Great Poland to the US after failed uprising in 1846 against Prussia in order to avoid possible arrest.
PIYUK T.G.
doaj  

RU CAMPUS UPRISING [PDF]

, 2016
RU campus uprising, 1970https://digitalcommons.rockefeller.edu/celebration_of_hirsch/1011/thumbnail ...
The Rockefeller University
core  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source