Results 61 to 70 of about 29,313 (286)

Postulaty religijne w wystąpieniach kozackich pierwszej połowy XVII wieku

open access: yesPoznańskie Studia Slawistyczne, 2016
This paper focuses mostly on the religious aspects of the Cossacks’ uprisings in the first half of 17th century (mainly the 1625, 1630, 1637 and 1638 uprisings), and discusses their impact on the origins, the course and following peace negotiations as ...
Mariusz Robert Drozdowski
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

« Alzarse » : les formes d’une pratique, depuis l’époque des palenques jusqu’à l’extinction des derniers groupes de guérilleros anticastristes

open access: yesNuevo mundo - Mundos Nuevos, 2008
This article hinges upon historical analysis to describe the complexity of the alzamientos ("uprisings") that took place in Cuba between 1959 and 1965 by reflecting on the way in which they intermingled practices anchored in long-term local history ...
Vincent Bloch
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Artivistic interventions as humorous re-appropriations

open access: yesThe European Journal of Humour Research, 2015
The article reflects on the synergic interaction of artistic creativity and activist engagement through a humorous approach of some contemporary civilian protest actions in Slovenia.
Aldo Milohnic
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

XIX. Yüzyılın İkinci Yarısında Anadolu'daki Ermeni Terörü (Diyarbakır, Arapgîr, Harput, Merzifon, Havza, Amasya ve Malatya'da Meydana Gelen Ermeni Ayaklanmaları Hakkında Bir Lâyiha)

open access: yesBelgeler, 2008
Ermeni meselesi ve pek çok konuya ilişkin arşivlerimizde zengin bilgiler bulunmaktadır. Nitekim bu haliyle arşivlerimiz bütün dünya devletlerini yakından ilgilendiren bir hüviyettedir.
Ahmet Halaçoğlu
doaj  

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