Results 61 to 70 of about 29,313 (286)
Postulaty religijne w wystąpieniach kozackich pierwszej połowy XVII wieku
This paper focuses mostly on the religious aspects of the Cossacks’ uprisings in the first half of 17th century (mainly the 1625, 1630, 1637 and 1638 uprisings), and discusses their impact on the origins, the course and following peace negotiations as ...
Mariusz Robert Drozdowski
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
This article hinges upon historical analysis to describe the complexity of the alzamientos ("uprisings") that took place in Cuba between 1959 and 1965 by reflecting on the way in which they intermingled practices anchored in long-term local history ...
Vincent Bloch
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Artivistic interventions as humorous re-appropriations
The article reflects on the synergic interaction of artistic creativity and activist engagement through a humorous approach of some contemporary civilian protest actions in Slovenia.
Aldo Milohnic
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Ermeni meselesi ve pek çok konuya ilişkin arşivlerimizde zengin bilgiler bulunmaktadır. Nitekim bu haliyle arşivlerimiz bütün dünya devletlerini yakından ilgilendiren bir hüviyettedir.
Ahmet Halaçoğlu
doaj

