Results 121 to 130 of about 628,251 (363)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Baptist Doctrine Upset [PDF]

, 1930
https://digitalcommons.acu.edu/crs_books/1024/thumbnail ...
Borden, Eli Monroe
core   +1 more source

Figure S2 from Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks

, 2023
Aashish Soni, Fanghua Li, You Wang, Martha Grabos, Lisa Marie Krieger, Shipra Chaudhary, Mohammad Sharif Mortoga Hasan, Mansoor M. Ahmed, C. Norman Coleman, Beverly A. Teicher, Richard Piekarz, Dian Wang, George Iliakis   +12 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Research program to develop a technology improvement program for closed die forging Final report [PDF]

Upset forging tests on aluminum and titanium alloys and maraging steel using high temperature ...
Anderson, P. E., Davis, L. W., Long, J. R.   +2 more
core   +1 more source

Strategic Diversity in Union Political Action: Implications for the 1992 House Elections [PDF]

, 1992
[Excerpt] The purpose of this paper is to explore labor\u27s strategic options in the 1992 elections. We will focus on House races because the diversity in political strategies among unions is most apparent there.
Hurd, Richard W, Sohl, Jeffrey E
core   +1 more source

Scaling in Tournaments

, 2006
We study a stochastic process that mimics single-game elimination tournaments. In our model, the outcome of each match is stochastic: the weaker player wins with upset probability ...
Ben-Naim, E., Redner, S., Vazquez, F.
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The study on the properties of AISI 4140 and AISI 1040 steel rods welded by friction welding

KKU Engineering Journal, 2014
This paper is aimed to investigate the properties of joint between AISI 4140 and AISI 1040 welded by friction welding. The specimens were prepared in round shape of 13 mm diameter and 100 mm long.
Thanee Toomprasen, Chawalit Thinvongpituk, Sukangkana Talangkun   +2 more
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source