Results 131 to 140 of about 628,251 (363)

Gender Dependent Flashbulb Memories of Sexual vs. Emotional Infidelity [PDF]

open access: yes, 2013
Research has suggested that males are more aroused and upset when their partner commits sexual infidelity and women are more aroused and upset when their partner commits emotional infidelity (Schutzwhol, 2005); however, most studies used forced choice ...
Fisher, Christine Therese
core   +1 more source

Single-event upset simulation and detection in configuration memory

open access: yesFrontiers in Space Technologies
Single-event upsets (SEUs) from radiation strikes in configuration memory are potentially catastrophic due to their widespread effects. For field-programmable gate arrays (FPGAs), faults in configuration memory propagate into the implemented logic design
Hezekiah Austin   +8 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Modeling of spacecraft charging [PDF]

open access: yes, 1977
Three types of modeling of spacecraft charging are discussed: statistical models, parametric models, and physical models. Local time dependence of circuit upset for DoD and communication satellites, and electron current to a sphere with an assumed Debye ...
Whipple, E. C., Jr.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Unsuccessful Concepts for Aircraft Wake Vortex Minimization [PDF]

open access: yes
Exploratory concepts are described which were investigated to achieve a reduction in the vortex induced rolling upsets produced by heavy aircraft trailing vortexes.
Dunham, R. E., Jr.
core   +1 more source

Home - About - Disclaimer - Privacy