Results 181 to 190 of about 632,890 (360)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Anti-inflammatory therapies to prevent cardiovascular events: systematic review and network meta-analysis of randomised controlled trials. [PDF]

Front Cardiovasc Med
Boczar KE, Pearson AL, Hakimjavadi R, Shin S, Shahab S, Geejo A, Visintini SM, Fehlmann CA, Bezzina KA, Beanlands RSB, Wells GA.   +10 more
europepmc   +1 more source

Single-event upset simulation for 6-transistor SRAM cell irradiated with high energy ions / V. N. Yuvchenko, S. A. Miskiewicz, F. F. Komarov [PDF]

Ювченко, В. Н., Мискевич, С. А., Комаров, Ф. Ф.   +2 more
openalex  

Letter to the Editor commenting on “Effect of Friction and Specimen Geometry on the Ductile Fracture in Upset Forging” (Samanta, S. K., 1975, ASME J. Eng. Mater. Technol., 97, pp. 14–20) [PDF]

, 1975
M. L. Williams, I. Finnie
openalex   +1 more source

Figure S2 from Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks

, 2023
Aashish Soni, Fanghua Li, You Wang, Martha Grabos, Lisa Marie Krieger, Shipra Chaudhary, Mohammad Sharif Mortoga Hasan, Mansoor M. Ahmed, C. Norman Coleman, Beverly A. Teicher, Richard Piekarz, Dian Wang, George Iliakis   +12 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

What do people want to know about another person? The answer depends on whether that person is an adult or a child. [PDF]

PLoS One
Billet MI, Hohm I, Dunn RM, Hofer MK, Sidloski B, Schaller M.   +5 more
europepmc   +1 more source

Single Event Upsets in RAMs Induced by Protons at 4.2 GeV and Protons and Neutrons below 100 MeV

, 1980
C. S. Guenzer, R.G. Allas, A.B. Campbell, J. M. Kidd, E.L. Petersen, N. Seeman, E. A. Wolicki   +6 more
openalex   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Emotion regulation strategies among young men in rural areas and urban informal settlements in South Africa: a qualitative exploratory study. [PDF]

Vulnerable Child Youth Stud
Nyoni P, Tomita A, Mkhwanazi S, Gibbs A.
europepmc   +1 more source