Results 111 to 120 of about 2,742,094 (289)

Nitrogen forms affect root structure and water uptake in the hybrid poplar [PDF]

, 2011
The study analyses the effects of two different forms of nitrogen fertilisation (nitrate and ammonium) on root structure and water uptake of two hybrid poplar (Populus maximowiczii x P. balsamifera) clones in a field experiment.
A Clemensson-Lindell, A Hodge, A Karacic, AH Fitter, AH Fitter, B Huang, C Glynn, CC Kern, Christian Messier, D Guo, DA Rose, DI Dickmann, DM Eissenstat, DM Eissenstat, E Salas, F Ripullone, Frank Berninger, GA Bauer, GB West, H Coners, H Ozier-Lafontaine, H Poorter, HP Harvey, HP Harvey, J Lopez-Bucio, J Lynch, JA Parkinson, JEK Cooke, JS King, JS King, KS Pregitzer, KS Pregitzer, KS Pregitzer, L Coll, Lluís Coll, M Noordwijk van, MD Coleman, P Armengaud, R Driesche Van den, R Fujimaki, RMA Block, S Delagrange, Susy Domenicano, T Ericsson, T Sakuratani, TJ Albaugh, WTM Woolfolk, X Min   +47 more
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Bioavailability of pesticides in freshwater sediments [PDF]

, 2007
In ecological risk assessment standardized sediment toxicity tests are used to predict the hazard of chemicals for sediment-living organisms. Feeding is a prerequisite in these long-term tests to avoid starvation of test organisms.
Åkerblom, Nina
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Effects of Source on the Nitrogen Uptake, Allocation Patterns, and Performance of Strawberry (Fragaria × ananassa Duch.): A ¹⁵N-Tracer Study

Plants
Nitrogen (N) is an essential determinant of strawberry growth and productivity. However, plants exhibit varying preferences for sources of nitrogen, which ultimately affects its use efficiency.
Sirajo Salisu Jibia, Kanokwan Panjama, Chaiartid Inkham, Takashi Sato, Norikuni Ohtake, Soraya Ruamrungsri   +5 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Collaboration for Increasing Influenza Vaccination in Children (CIIVIC): a meeting report

Australian and New Zealand Journal of Public Health, 2021
Daniel A. Norman, Samantha J. Carlson, Jane Tuckerman, Jessica Kaufman, Hannah C. Moore, Holly Seale, Julie Leask, Helen Marshall, Catherine Hughes, Christopher C. Blyth, Margie Danchin, CIIVIC: The Collaboration for Increasing Influenza Vaccination in Children   +11 more
doaj   +1 more source

Comparative Toxicokinetics and Biomarker Responses of Typical Psychiatric Pharmaceuticals in Daphnia magna

Toxics
The widespread availability and pseudo-persistence of typical psychiatric pharmaceuticals (PDs) can have serious impacts on aquatic ecosystems and even human health.
Haohan Yang, Hao Xing, Zhuoyu Chen, Linghui Kong, Hanyu Jiang, Tengyi Zhu   +5 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source