Results 141 to 150 of about 8,610 (171)

Antisense RNA Interference-Enhanced CRISPR/Cas9 Base Editing Method for Improving Base Editing Efficiency in Streptomyces lividans 66.

ACS Synthetic Biology, 2021
CRISPR/Cas9-mediated base editors, based on cytidine deaminase or adenosine deaminase, are emerging genetic technologies that facilitate genomic manipulation in many organisms.
Yuer Zhang, Kaiyue Yun, Huamei Huang, R. Tu, Erbing Hua, Meng Wang   +5 more
semanticscholar   +1 more source

Distance-Based Biosensor for Ultrasensitive Detection of Uracil-DNA Glycosylase Using Membrane Filtration of DNA Hydrogel.

ACS Sensors, 2021
In the deoxyribonucleic acid (DNA) repair pathways, DNA repair enzymes have great significance for genomic integrity. As one important initiator of the base-excision repair pathway, the aberrant activity of uracil-DNA glycosylase (UDG) is closely ...
Chao Jiang, Fangfang Wang, Kexin Zhang, Tiantian Min, Desheng Chen, Y. Wen   +5 more
semanticscholar   +1 more source

[Uracil-DNA glycosidase studied with an immune serum].

Tsitologiia, 1985
Immune antiserum to uracil-DNA glycosylase was obtained by immunizing rabbits with an enzyme isolated from the rat liver. Antiserum was found to suppress the activity of uracil-DNA glycosylase not only in the extracts of rat liver, but also in the extracts of brain, cardiac muscle, kidney, spleen, thymus of rats, and in those of human placenta too ...
O N, Aprelikova, Z I, Uspenskaia, G S, Lebedeva, V M, Mikhaĭlov, N V, Tomilin   +4 more
openaire   +1 more source

Enzymic degradation of uracil-containing DNA. 3. Partial purification and characterization of a uracil DNA N-glycosidase from Bacillus subtilis

Biochemistry, 1977
Richard Cone, James Duncan, Lenore Hamilton, Errol C. Friedberg   +3 more
openaire   +1 more source

Inroads into base excision repair II. The discovery of DNA glycosylases. "An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues," Proc. Nat. Acad. Sci. USA, 1974.

DNA Repair, 2004
E. Friedberg, T. Lindahl
semanticscholar   +1 more source

In vivo synthesis and properties of uracil-containing DNA

Nature, 1978
H. Warner, B. Duncan
semanticscholar   +1 more source

Glycosidase activated prodrugs for targeted cancer therapy

Chemical Society Reviews, 2022
Harlei Martin, , Thorfinnur Gunnlaugsson
exaly  

Glycosidase-targeting small molecules for biological and therapeutic applications

Chemical Society Reviews, 2023
Injae Shin
exaly  

A novel Family V uracil DNA glycosylase from Sulfolobus islandicus REY15A.

DNA Repair, 2022
Mai Wu, Likui Zhang, K. Dong, Y. Gong, Xipeng Liu   +4 more
semanticscholar   +1 more source

Molecular basis of base substitution hotspots in Escherichia coli

Nature, 1978
C. Coulondre, Jeffrey H. Miller, P. Farabaugh, W. Gilbert   +3 more
semanticscholar   +1 more source