Results 221 to 230 of about 86,414 (313)
Tautomerization‐assisted oxidation of molnupiravir by superoxide (O2•−) in aprotic DMF. The thermodynamically favored oxime tautomer of the N4‐hydroxycytosine moiety forms a prereactive complex (PRC) with O2•− through hydrogen‐bonding interactions.
Tatsushi Nakayama, Kaisei Hara
wiley +1 more source
On the ozonation of anti-SARS-CoV-2 substances and their nucleoside analogues for mechanistic understanding of the ozone induced transformation using HPLC-ESI-Q-TOF-HRMS. [PDF]
Bartels I +3 more
europepmc +1 more source
Advances in cholesterol and lipoproteins detection for healthcare: A review
Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta +7 more
wiley +1 more source
The <i>AfldrnA</i> Transcription Factor Is a Pivotal Regulator of the Conidiation-Sclerotial Formation Balance in <i>Aspergillus flavus</i>. [PDF]
Abdo-Elgabbar MA +5 more
europepmc +1 more source
Abstract During the COVID‐19 pandemic, heat stress (HS) was a serious occupational risk for health‐care workers (HCWs) wearing personal protective equipment, which limits heat dissipation and increases the risk of kidney injury. In this exploratory study, we assessed HS‐related changes in the urinary metabolites of 38 HCWs working at mobile COVID‐19 ...
Cheng‐Yu Ting +9 more
wiley +1 more source
In the TALENTs trial, 19‐week exogenous nucleotide supplementation produced UA‐PRS‐dependent anti‐aging responses: reduced DNA methylation age in High‐PRS individuals and preserved telomere length with improved immune–inflammatory profiles in Low‐PRS individuals, supporting precision nutrition for healthy aging.
Ruisheng Fu +6 more
wiley +1 more source
Effects of thymidylate synthase inhibitors differ in genomic uracilation and mutagenic potential. [PDF]
Holub E +7 more
europepmc +1 more source
A SMUG1 Inhibitor Modulates the Excision of Pyrimidine DNA Damage. [PDF]
Thacker PS +8 more
europepmc +1 more source
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro +4 more
wiley +1 more source
Association of DPYD rs4294451, plasma uracil concentration, and sex with 5-fluorouracil exposure in patients with gastrointestinal cancer. [PDF]
Brooks GA +12 more
europepmc +1 more source

