Discovery of Tyrosinase Inhibitors from <i>Lysinibacillus</i> sp. JNUCC 52 via Genome Mining, Secondary Metabolites Profiling, and In Silico Analysis. [PDF]
Liang X, Xu Y, Hyun CG.
europepmc +1 more source
Time‐dependent fermentation caused dynamic changes in the bioactive constituents of white corn steep liquor and improved its antioxidant, antidiabetic, and antiobesogenic activities in vitro. ABSTRACT The present study investigated the effect of crude fermentation on white corn steep liquor and its bioactive constituents in the management of metabolic ...
Lemohang Gumenku +5 more
wiley +1 more source
A Single-Enzyme Activated CRISPR-Cas12a Nano System via Subtly Balanced dsDNA for Kinetic-Gated UDG Detection and Spatiotemporal Cellular Imaging. [PDF]
Dong K +12 more
europepmc +1 more source
Escherichia coli double-strand uracil-DNA glycosylase (Dug) was purified to apparent homogeneity from bacteria that were defective in uracil-DNA glycosylase (Ung). After cloning the dug gene, recombinant Dug was overexpressed, purified, and characterized
Sung, Jung-Suk
core
Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li +17 more
wiley +1 more source
Exploring an azo-uracil based nickel(ii) complex for anticancer and phosphatase like activities. [PDF]
Ghosh S +4 more
europepmc +1 more source
Identification of Natural and Artificial Modifications in DNA at the Nanometer Level
Short single‐ and double‐stranded DNA sequences with natural and artificial markers are examined at ambient conditions using TERS to identify and localize the labelled nucleobases. The differences between single‐ and double‐stranded DNA should provide clear experimental evidence of the extreme surface sensitivity of TERS.
Tanja Deckert‐Gaudig +4 more
wiley +1 more source
Ru Nanoparticles Ligated by an N-Heterocyclic Carbene Derived from Uracil Nucleoside as Selective Antimicrobial Agents. [PDF]
Sánchez A +9 more
europepmc +1 more source
ABSTRACT Since the 2018 valsartan recall, the genotoxic impurity N‐nitrosodimethylamine (NDMA) has been frequently detected in various pharmaceuticals. Matrix variability often complicates routine testing, requiring customized analyses. We developed a universal LC–MS/MS method enabling consistent NDMA detection across diverse pharmaceuticals ...
Byungchan An +9 more
wiley +1 more source
Turning on Protein Function Inhibited by DNA Aptamers Employing a Covalent DNA-Binding Protein. [PDF]
Kanazu T +6 more
europepmc +1 more source

