Results 191 to 200 of about 333,342 (343)

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

open access: yesCell Proliferation, EarlyView.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng   +10 more
wiley   +1 more source

The Monster ‘Within’: Capitalist Urbanization as Geometabolic Escalation

open access: yesDevelopment and Change, EarlyView.
ABSTRACT This article challenges prevailing approaches to urban sustainability by reconceptualizing capitalist urbanization as a planetary process of geometabolic escalation. Hegemonic visions of sustainable cities render invisible the non‐city sociometabolic preconditions and consequences of urban life under capitalism.
Neil Brenner, Swarnabh Ghosh
wiley   +1 more source

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