Results 171 to 180 of about 689,520 (364)

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Potential of aryl–urea–benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease

, 2015
Belma Zengin Kurt, Işıl Gazioğlu, Livia Basile, Fatih Sönmez, Tiziana Ginex, Mustafa Küçükislamoğlu, Salvatore Guccione   +6 more
openalex   +1 more source

Synthesis of Urea and Carbamate Glycosides Employing Unprotected Carbohydrates [PDF]

, 2011
Yoshiyasu Ichikawa, Shohei Kusaba, Takahiro Minami, Yumiko Tomita, Keiji Nakano, Hiyoshizo Kotsuki   +5 more
openalex   +1 more source

Detection of Helicobacter pylori infection by ¹⁴ C urea breath test in asymptomatic adults: A pilot study in Kanbauk village tract [PDF]

, 2021
Aye Min Soe, Khun Nyi Nyi, Pann Ei San
openalex   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Whole mount electron microscopy of fibril-rings in alkali-urea treated salivary gland chromosomes of Drosophila melanogaster

, 2009
Veikko Sorsa
openalex   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

Urea-Tethered Porous Organic Polymer (POP) as an Efficient Heterogeneous Catalyst for Hydrogen Bond Donating Organocatalysis and Continuous Flow Reaction

Hydrogen bond donating (HBD) heterogeneous organocatalysis has come to light as a powerful surrogate to Lewis acid activation toward manufacturing biologically important C–C bonds. Notwithstanding the emergence of urea as a functionally diverse moiety to
Gourab K. Dam (16375529), Vartika Jaiswal (17969146), Sujit K. Ghosh (726424), Sumanta Let (9345208)   +3 more
core   +1 more source

Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review). [PDF]

Int J Mol Med
Zhu B, Wang C, Liu P, Qu Z, Qi R, Chen S, Niu H.   +6 more
europepmc   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source