Results 191 to 200 of about 689,520 (364)

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Circadian Modulation of Protein Catabolism: Insight from a Population Study. [PDF]

Nutrients
Kafader ML, Sare S, Zandonà M, Giorno RD, Garo ML, Bonetti S, Gabutti L.   +6 more
europepmc   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

Additional file 2 of Elevated blood urea nitrogen is associated with recurrence of post-operative chronic subdural hematoma

, 2020
Ning Wang, Jiangnan Hu, Anthony Oppong‐Gyebi, Xuanhao Zhu, Yihao Li, Jianjing Yang, Linhui Ruan, Qichuan Zhuge, Sheng Ye   +8 more
openalex   +1 more source

Urea Inhibits the Formation of Environmentally Persistent Free Radicals as well as Accelerates Their Decay. [PDF]

ACS Omega
Nde D, Foley F, Kizilkaya O, Lard M, Richmond-Bryant J, Khachatryan L, Lomnicki S, Sprunger P, Cormier SA.   +8 more
europepmc   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

Efficiency of the sources and urea rates on structural characteristics, accumulation and nutritive value of forage massai grass

, 2014
Camila de Lizier Mesquita Pires
openalex   +1 more source

Synergistic application of controlled-release urea and potassium chloride to enhance wheat yield and nutrient use efficiency. [PDF]

Front Plant Sci
Yang X, Li J, Zhang W, Jia W, Li Z, Geng J, Lei S, Li H, Zhang Q, Lang Y, Huo X.   +10 more
europepmc   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

Urea and mineral salt in supplements for crossbred dairy cows

, 2014
César Roberto Viana Teixeira
openalex   +1 more source