Results 71 to 80 of about 2,610,885 (275)

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

Advanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu, Hsi‐wen Wu, Xiao Wang, Jie Zhang   +3 more
wiley   +1 more source

Exploring RNA therapeutics for urea cycle disorders [PDF]

RNA has triggered a significant shift in modern medicine, providing a promis-ing way to revolutionize disease treatment methods. Different therapeutic RNA modalities have shown promise to replace, supplement, correct, suppress,or eliminate the expression
Richard, Eva, Desviat, Lourdes R., Richard Rodríguez, Eva María, Martínez-Pizarro, Ainhoa, Martínez Pizarro, Ainhoa, Ruiz Desviat, Lourdes, Desviat, Lourdes R   +6 more
core   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington\u27s disease mouse model

, 2017
Huntington\u27s disease (HD) is caused by a mutation in the huntingtin gene (HIT), resulting in profound striatal neurodegeneration through an unknown mechanism.
Stubbs, Andrew D., Halbesma, Timothy, Andrew D. Stubbs, Hunter K. Holt, K. Grace Tipps, Alexander Osmand, Kwakye, Gunnar F., Bradley, Emma M., Miles Bryan, Karrie Dudek, Umashanker, Preethi, Gunnar F. Kwakye, Fisher, Nicole, Terry Jo V. Bichell, Bryan, Miles, Michal Wegrzynowicz, Andrew M. Tidball, Uhouse, Michael A., Dudek, Karrie, Tipps, K. Grace, Bichell, Terry Jo, Preethi Umashanker, Aschner, Michael, Michael A. Uhouse, Bowman, Aaron B., M. Diana Neely, Colbran, Roger J., Michael Aschner, Emma M. Bradley, Horning, Kyle, Holt, Hunter K., Kyle Horning, Aaron B. Bowman, Tidball, Andrew M., Timothy Halbesma, Alba Di Pardo, Vittorio Maglione, Neely, M. Diana, Roger J. Colbran, Nicole Fisher, Wegrzynowicz, Michal   +40 more
core   +1 more source

N-acetylglutamate synthetase deficiency - literature review

Journal of Education, Health and Sport
Introduction and Objective: N-Acetylglutamate Synthetase Deficiency (NAGSD) is a rare urea cycle disorder, primarily caused by autosomal recessive genetic mutations. Most affected individuals are homozygous for the disease-causing allele.
Krystian Wdowiak, Agnieszka Maciocha, Julia Wąż, Aleksandra Witas, Justyna Drogoń, Weronika Chachaj, Natalia Szymkowiak, Ewa Gardocka   +7 more
doaj   +1 more source

Strong Fully Reprocessable Engineered Wood Composites

Advanced Materials, EarlyView.
Engineering a hyperbranched adhesive with complementary imine‐bond and hydrogen‐bond networks, combining it with wood particles to fabricate the wood composite (WP/HTP) under mild hot‐pressing conditions. The WP/HTP exhibits 100% mechanical strength recovery after three cycles of reprocessing, and the reprocessed modulus of rupture (MOR) and modulus of
Xilin Zhang, Zheng Liu, Zhezhe Zhou, Mark Lynch, Jianzhang Li, Paulomi Burey, Jingchao Li, Cheng Zhang, Qiang Gao, Pingan Song   +9 more
wiley   +1 more source

Ionic Cocrystal Programming of Spatial Ionic Organization in Carbon Nitrides Enables Highly Efficient H2O2 Photosynthesis

Advanced Materials, EarlyView.
Ionic cocrystal‐programmed ionic organization establishes a general strategy for electrostatic programming in polymeric photocatalysts. ABSTRACT Controlling the spatial organization of ions in polymeric photocatalysts remains a fundamental challenge for optimizing charge transport and catalytic selectivity in solar‐driven hydrogen peroxide (H2O2 ...
Anna Lo Presti, Zahra Hajiahmadi, Sam A. J. Hillman, Mu Xiao, James R. Durrant, Thomas D. Kühne, Christian Mark Pelicano   +6 more
wiley   +1 more source

Role of carglumic acid in the treatment of acute hyperammonemia due to N-acetylglutamate synthase deficiency

Therapeutics and Clinical Risk Management, 2011
Johannes HäberleKinderspital Zürich, Abteilung Stoffwechsel, Zürich, SwitzerlandAbstract: N-acetylglutamate synthase (NAGS) deficiency is a rare inborn error of metabolism affecting ammonia detoxification in the urea cycle. The
Häberle J
doaj  

Pulsed Oxidative–Reductive Electrolysis Over Dual Cu and Co Single‐Atom Sites for Urea Electrosynthesis

Advanced Materials, EarlyView.
Alternating oxidative–reductive pulses synchronize CO2‐derived *CO and NH3‐derived *NHx intermediates over dual Cu and Co single‐atom sites, enabling urea and ethyl urea formation with a total C─N Faradaic efficiency of 42 ± 4%. In situ spectroscopy and theoretical calculations elucidate complementary Cu and Co functions, while oxidative controls ...
Putri Ramadhany, Peiqi Qiu, Thành Trần‐Phú, Denny Gunawan, Bernt Johannessen, Rosalie K. Hocking, Yan Jiao, Rose Amal, Rahman Daiyan   +8 more
wiley   +1 more source

Enhanced Xylene Sensing Performance of Fe‐Doped NiO Nanosheet Arrays via In Situ Growth

Advanced Materials Interfaces, EarlyView.
Xylene is a hazardous volatile organic compound (VOC) widely present in industrial environments, and achieving sensitive and stable detection of xylene remains a significant challenge for gas sensors. Here, a one‐step hydrothermal route was employed to in situ grow p‐type Fe‐doped NiO nanosheet arrays on ceramic tubes for xylene detection.
Yinglin Wang, Yitong Jiang, Zhaohui Lei, Yantong Meng, Wanting Cui, Pengfei Cheng, Ye Tian, Bowen Fang, Xidong Hao, Shanfu Sun, Yiyang Xu, Ning Sun, Zhi Weng   +12 more
wiley   +1 more source