Hypoaminoacidemia and Pyroglutamic Aciduria: Potential Biomarkers in Malnutrition‐Related Hyperammonemia [PDF]
JIMD ReportsHyperammonemia is a medical emergency, and the cause must be identified quickly in order to treat appropriately. Malnutrition is a known risk factor for hyperammonemia; however, there are limited reliable lab indicators used to identify malnutrition ...
M. M. Crenshaw +12 more
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Acute pediatric hyperammonemia: current diagnosis and management strategies
Hepatic Medicine: Evidence and Research, 2018 Nadia Savy,1 David Brossier,2 Catherine Brunel-Guitton,1 Laurence Ducharme-Crevier,1 Geneviève Du Pont-Thibodeau,1 Philippe Jouvet1 1Department of Pediatrics, CHU Sainte-Justine, University of Montreal, Montreal, QC, Canada; 2Department of ...
David Brossier +2 more
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Clinical and biochemical factors associated with hyperammonemia in inpatients with mental disorders treated with valproic acid: a cross-sectional analysis [PDF]
Therapeutic Advances in PsychopharmacologyBackground: Valproic acid (VPA)-induced hyperammonemia is a common condition whose clinical presentations can range from asymptomatic cases to severe hyperammonemic encephalopathy. This can happen at any stage of treatment and is difficult to predict, as
Ilaria Riboldi +5 more
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Sarcopenia modelling by portal vein ligation inducing hyperammonemia in rats. [PDF]
PLoS ONESarcopenia is a progressive muscle wasting condition often associated with hyperammonemia. However, no approved animal models of sarcopenia with hyperammonemia were reported.
Maria Nadinskaia +10 more
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Hyperammonemia Post Lung Transplantation: A Review
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2020 Hyperammonemia is the pathological accumulation of ammonia in the blood, which can occur in many different clinical settings. Most commonly in adults, hyperammonemia occurs secondary to hepatic dysfunction; however, it is also known to be associated with
Robert F Leger, Ksenia D Guvakova
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Hyperammonemia in patients receiving valproic acid in the hospital setting: A retrospective review [PDF]
Mental Health Clinician, 2021 Introduction: Valproic acid (VPA) is widely used for the treatment of epilepsy, migraine, and a variety of psychiatric conditions. The reported incidences of hyperammonemia induced by VPA use is variable.
Tressa McMorris, PharmD, BCPS +3 more
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Impact of non-hepatic hyperammonemia on mortality in intensive care unit patients: a retrospective cohort study [PDF]
The Korean Journal of Internal Medicine, 2021 Background/Aims The effect of hyperammonemia on the mortality in patients with liver cirrhosis is well documented. However, little is known about the impact of hyperammonemia on mortality among intensive care unit patients without hepatic disease.
Jae Heon Kim +8 more
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New developments in the treatment of hyperammonemia: emerging use of carglumic acid
International Journal of General Medicine, 2011 Marta Daniotti1, Giancarlo la Marca2, Patrizio Fiorini1, Luca Filippi11Neonatal Intensive Care Unit, Department of Perinatal Medicine, “A. Meyer” University Children’s Hospital, Florence, Italy; 2Mass Spectrometry, Clinical ...
Luca Filippi, Giancarlo La Marca
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A Case of Severe Hyperammonemic Encephalopathy Caused by Urinary Tract Infection in Obstructive Uropathy [PDF]
Childhood Kidney Diseases, 2021 Hyperammonemia is mainly caused by diseases related to liver failure. However, there are also non-hepatic causes of hyperammonemia, such as urinary tract infection (UTI) due to urease-producing organisms.
Bo Gyung Mun +3 more
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Journal of Investigative Medicine High Impact Case Reports, 2022 Mycoplasma and Ureaplasma infections have been described as a cause of hyperammonemia syndrome leading to devastating neurological injury in the post-transplant period, most commonly in lung transplant recipients.
Steven M. Phillips DO +8 more
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