Results 31 to 40 of about 12,857 (206)
Methamphetamine-induced encephalopathy in the absence of hyperammonemia
BMC Psychiatry, 2023 Background Methamphetamine is an addictive drug with various effects on the neurotransmitters in the central nervous system. Methamphetamine-induced encephalopathy in the absence of hyperammonemia presents a unique challenge in a clinical setting ...
Jessica M Rabbany +4 more
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Internal Medicine, 2023 A 91-year-old woman was brought to our hospital with altered consciousness. Blood tests showed an increased ammonia level of 468 μg/dL and a normal liver function. Chest computed tomography showed massive right pleural effusion with loculation. We immediately performed chest drainage using two drainage tubes. The pleural effusate pH was 8.5.
Wada, Hiroshi +2 more
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O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis
Nature Communications, 2022 Hyperammonemia occurs in liver diseases affecting ureagenesis, and is life-threatening. Here, the authors show that liver UDP-GlcNAc is increased during hyperammonemia, leading to O-GlcNAcylation of the rate-limiting ureagenesis enzyme CPS1, that ...
Leandro R. Soria +21 more
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Hyperammonemia presenting as opsoclonus–myoclonus–ataxia–tremor syndrome: A case report
Annals of Movement Disorders, 2022 Opsoclonus myoclonus syndrome (OMS) is a rare autoimmune condition occurring due to Purkinje cell degeneration due to remote aetiology. Most often it occurs as a paraneoplastic syndrome.
Sandhya Manorenj, Govind Verma
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A Newborn with Hypothermia and Hyperammonemia [PDF]
Clinical Chemistry, 2018 A full-term small gestational age female infant was transferred to the NICU for hypothermia and seizure-like activity. In the first 10 h of life, the infant had difficulty feeding and developed mild hypothermia, which resolved after placing her on a radiant warmer.
Khanh Quynh N, Nguyen +2 more
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Non-cirrhotic hyperammonemia in a newly diagnosed diabetic patient presenting in diabetic ketoacidosis [PDF]
, 1970 Hyperammonemia, a known cause of encephalopathy, is commonly seen in patients with liver disease. Non-cirrhotic hyperammonemia is an uncommon condition. Patients with uncontrolled diabetes can have elevated levels of ammonia.
Josephine, Blessy +2 more
core +1 more source
Hyperammonemia in patients on Valproic Acid therapy in a tertiary care hospital of Karachi
Khyber Medical University Journal, 2023 OBJECTIVE: to assess the incidence of hyperammonemia in patients receiving valproic acid (VPA) therapy. METHODS: This cross-sectional study was conducted at the Department of Neurology, Ziauddin Medical University and Hospital, Karachi, for six months ...
Iqra Ali +2 more
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Hyperammonemia and proteostasis in cirrhosis [PDF]
Current Opinion in Clinical Nutrition & Metabolic Care, 2018 Skeletal muscle loss or sarcopenia is a frequent complication of cirrhosis that adversely affects clinical outcomes. As skeletal muscle is the largest store of proteins in the body, proteostasis or protein homeostasis is required for maintenance of muscle mass. This review will focus on disordered skeletal muscle proteostasis in liver disease.Increased
Srinivasan, Dasarathy, Maria, Hatzoglou
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Asthenia and fatigue in hyperammonemia: etiopathogenesis and methods of correction
Медицинский совет, 2022 Asthenia and fatigue are the most common syndromes in patients with liver disease, which significantly affects their quality of life. The prevalence of fatigue in chronic liver diseases is from 50% to 85%.
E. Yu. Plotnikova +2 more
doaj +1 more source
A zebrafish model of hyperammonemia [PDF]
Molecular Genetics and Metabolism, 2014 Hyperammonemia is the principal consequence of urea cycle defects and liver failure, and the exposure of the brain to elevated ammonia concentrations leads to a wide range of neuro-cognitive deficits, intellectual disabilities, coma and death. Current treatments focus almost exclusively on either reducing ammonia levels through the activation of ...
B. Feldman, M. Tuchman, L. Caldovic
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