Results 11 to 20 of about 9,482 (191)
Multiple Asparaginase Infusions Cause Increasingly Severe Acute Hyperammonemia
Medical Sciences, 2022 Adverse reactions during and shortly after infusing asparaginase for the treatment of acute lymphoblastic leukemia can increase in severity with later doses, limiting further use and increasing relapse risk.
Randal K Buddington +2 more
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Hematology, 2023 Hyperammonemia is a rare and often fatal complication following the conditioning therapy in autologous and allogeneic stem cell transplant recipients. It is characterized by anorexia, vomiting, lethargy and coma without any other apparent cause.
Galina Tsykunova +6 more
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Molecular Genetics and Metabolism Reports, 2020 Hyperammonemia is a typical symptom of urea cycle disorders. While early-onset argininosuccinic aciduria (ASA) can often be detected by hyperammonemia, patients with late-onset ASA predominantly present with psychomotor retardation and mental disorders ...
Yoshimitsu Osawa +4 more
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Fatal Idiopathic Hyperammonemia after Induction Chemotherapy for Acute Myeloid Leukemia
Case Reports in Hematology, 2020 Idiopathic hyperammonemia is a rare but potentially fatal complication occurring in patients with acute leukemia or bone marrow transplantation. The role of some specific anticancer drugs may be discussed, but the etiology of hyperammonemia is often ...
Christophe Angelo +5 more
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Long-term N-carbamylglutamate treatment of hyperammonemia in patients with classic organic acidemias
Molecular Genetics and Metabolism Reports, 2021 Background: Classic organic acidurias (OAs) usually characterized by recurrent episodes of acidemia, ketonuria, and hyperammonemia leading to coma and even death if left untreated.
Ertugrul Kiykim +5 more
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Methamphetamine-induced encephalopathy in the absence of hyperammonemia
BMC Psychiatry, 2023 Background Methamphetamine is an addictive drug with various effects on the neurotransmitters in the central nervous system. Methamphetamine-induced encephalopathy in the absence of hyperammonemia presents a unique challenge in a clinical setting ...
Jessica M Rabbany +4 more
doaj +1 more source
Internal Medicine, 2023 A 91-year-old woman was brought to our hospital with altered consciousness. Blood tests showed an increased ammonia level of 468 μg/dL and a normal liver function. Chest computed tomography showed massive right pleural effusion with loculation. We immediately performed chest drainage using two drainage tubes. The pleural effusate pH was 8.5.
Wada, Hiroshi +2 more
openaire +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis
Nature Communications, 2022 Hyperammonemia occurs in liver diseases affecting ureagenesis, and is life-threatening. Here, the authors show that liver UDP-GlcNAc is increased during hyperammonemia, leading to O-GlcNAcylation of the rate-limiting ureagenesis enzyme CPS1, that ...
Leandro R. Soria +21 more
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Hyperammonemia presenting as opsoclonus–myoclonus–ataxia–tremor syndrome: A case report
Annals of Movement Disorders, 2022 Opsoclonus myoclonus syndrome (OMS) is a rare autoimmune condition occurring due to Purkinje cell degeneration due to remote aetiology. Most often it occurs as a paraneoplastic syndrome.
Sandhya Manorenj, Govind Verma
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