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Coordination Chemistry Reviews, 2021 
Conventional ureases possess dinuclear nickel active sites that are oxygen-stable and require a set of accessory proteins for metallocenter biosynthesis. By contrast, oxygen-labile ureases have active sites containing dual ferrous ions and lack a requirement for maturation proteins. The structures of the two types of urease are remarkably similar, with
Denis A. Proshlyakov +3 more
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Conventional ureases possess dinuclear nickel active sites that are oxygen-stable and require a set of accessory proteins for metallocenter biosynthesis. By contrast, oxygen-labile ureases have active sites containing dual ferrous ions and lack a requirement for maturation proteins. The structures of the two types of urease are remarkably similar, with
Denis A. Proshlyakov +3 more
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Soybean leaf urease: Comparison with seed urease
Physiologia Plantarum, 1983Soybeans, Glycine max (L.) Merr., from ureides for transport of nitrogen from the root nodule to the shoot. The most direct routes for ureide utilization include the degradation of ureide‐derived urea to NH3 and CO2. Ureolytic activity was found in leaf disks of soybean and exhbited optimal activity at pH 7 in the presence of a high concentration of ...
D. G. Blevins +3 more
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Nature, 1948 
IN a previous communication1, we were able to confirm that urease is present in the gastric mucosa and, to some extent, in the duodenal mucosa. It was pointed out that the amount of the ferment present in the whole stomach of an animal is sufficient to release enough ammonia from urea to neutralize large amounts of hydrochloric acid.
Philip G. Murphy +3 more
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IN a previous communication1, we were able to confirm that urease is present in the gastric mucosa and, to some extent, in the duodenal mucosa. It was pointed out that the amount of the ferment present in the whole stomach of an animal is sufficient to release enough ammonia from urea to neutralize large amounts of hydrochloric acid.
Philip G. Murphy +3 more
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2013 
Urease is a nickel-dependent enzyme that catalyzes the reaction of water with urea. The reaction initially produces ammonia and carbamate, which then spontaneously decomposes to yield another molecule of ammonia and hydrogen carbonate. The structure and function of ureases are described.
S. Benini +2 more
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Urease is a nickel-dependent enzyme that catalyzes the reaction of water with urea. The reaction initially produces ammonia and carbamate, which then spontaneously decomposes to yield another molecule of ammonia and hydrogen carbonate. The structure and function of ureases are described.
S. Benini +2 more
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2017 
Although the discovery of urease as the first enzyme for which nickel is essential for activity dates back to 1975, the rationale for Ni selection for the active site of this hydrolase has been only recently unraveled. The past 20 years have indeed witnessed impressive achievements in the understanding of the biological chemistry of Ni in urease, and ...
MAZZEI, LUCA +2 more
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Although the discovery of urease as the first enzyme for which nickel is essential for activity dates back to 1975, the rationale for Ni selection for the active site of this hydrolase has been only recently unraveled. The past 20 years have indeed witnessed impressive achievements in the understanding of the biological chemistry of Ni in urease, and ...
MAZZEI, LUCA +2 more
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Metal Ion Interactions with Urease and UreD-Urease Apoproteins
Biochemistry, 1996Klebsiella aerogenes urease in a Ni-containing enzyme (two Ni per alpha beta gamma unit) that is purified as an apoprotein from cells grown in Ni-free medium. Partial activation of urease and UreD-urease apoproteins is achieved in vitro by incubation in the presence of Ni(II) and CO2, whereas incubation of these proteins with Ni alone leads to the ...
Robert P. Hausinger, Il Seon Park
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Urological Research, 1979 
Urinary stones form as a consequence of urinary supersaturation. Supersaturation occurs as a result of elevated concentrations of urinary solutes. Dietary, metabolic, endocrine, hereditary, and infectious processes alter urinary solute concentrations. Struvite (MgNH4PO.
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Urinary stones form as a consequence of urinary supersaturation. Supersaturation occurs as a result of elevated concentrations of urinary solutes. Dietary, metabolic, endocrine, hereditary, and infectious processes alter urinary solute concentrations. Struvite (MgNH4PO.
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The Occurrence of Urease [PDF]
LETTERS on the occurrence of urease are printed in NATURE of August 11 and September 22. In the former, Prof. Werner reports that he has found urease in all the leguminous nodular growths he has tested; in the latter, Prof. Beijerinck describes how he has detected the enzyme in B. radicicola. Prof.
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