Results 51 to 60 of about 61,889 (286)

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Therapeutic Protection Against H. pylori Infection in Mongolian Gerbils by Oral Immunization With a Tetravalent Epitope-Based Vaccine With Polysaccharide Adjuvant

Frontiers in Immunology, 2019
Urease is an effective target for design of a therapeutic epitope vaccine against Helicobacter pylori (H. pylori). In our previous studies, an epitope vaccine CTB-UE containing Th and B epitopes from H.
Le Guo, Le Guo, Le Guo, Dantong Hong, Shue Wang, Fan Zhang, Feng Tang, Tao Wu, Yuankui Chu, Hongpeng Liu, Meng He, Hua Yang, Runting Yin, Kunmei Liu, Kunmei Liu   +14 more
doaj   +1 more source

Inhibition of ruminal urease [PDF]

, 1968
Rumen bacteria elaborate an enzyme, urease. Urease is capable of breaking down urea to ammonia and carbon dioxide. Rumen bacteria then incorporate the ammonia into new amino acids and bacterial protein. Thus, urea can be used as a non-nitrogen source
Brent, B.E., Adepoju, A., Richardson, D., Portela, F., B.E. Brent, A. Adepoju, F. Portela, D. Richardson   +7 more
core   +1 more source

Polymer Sequence Design of Zwitterionic Polymer/PEDOT:PSS Blend Films for Improved Charge Transport and Stability in Organic Electrochemical Transistors

Advanced Electronic Materials, EarlyView.
Solution blending of zwitterionic polymers with PEDOT:PSS provides a simple route to OECT materials with enhanced threshold voltage stability in biologically relevant environments. The polymer sequence alters outer‐domain structure within the preserved PEDOT:PSS framework, thereby tuning charge transport.
Wakana Takahashi, Aki Kashiwazaki, Masaya Mitsuishi, Shunsuke Yamamoto   +3 more
wiley   +1 more source

Sol-Gel Derived Adsorbents with Enzymatic and Complexonate Functions for Complex Water Remediation

Nanomaterials, 2017
Sol-gel technology is a versatile tool for preparation of complex silica-based materials with targeting functions for use as adsorbents in water purification. Most efficient removal of organic pollutants is achieved by using enzymatic reagents grafted on
Roman P. Pogorilyi, Ievgen Pylypchuk, Inna V. Melnyk, Yurii L. Zub, Gulaim A. Seisenbaeva, Vadim G. Kessler   +5 more
doaj   +1 more source

Disponibilidade de nitrato em solos brasileiros sob efeito da calagem e de fontes e doses de nitrogênio Nitrate availability in Brazilian soils under effect of liming and sources and amounts of nitrogen

Pesquisa Agropecuária Brasileira, 2000
Este trabalho objetivou avaliar os efeitos da calagem e de fontes e doses de N sobre a disponibilidade de nitrato, em amostras (020 cm) de solos brasileiros.
CARLOS ALBERTO SILVA, FABIANO RIBEIRO DO VALE   +1 more
doaj   +1 more source

Biomineralization in Cave Bacteria—Popcorn and Soda Straw Crystal Formations, Morphologies, and Potential Metabolic Pathways

Frontiers in Microbiology, 2022
Caves are extreme, often oligotrophic, environments that house diverse groups of microorganisms. Many of these microbes can perform microbiologically induced carbonate precipitation (MICP) to form crystalline secondary cave deposits known as speleothems.
Keegan Koning, Richenda McFarlane, Jessica T. Gosse, Sara Lawrence, Lynnea Carr, Derrick Horne, Nancy Van Wagoner, Christopher N. Boddy, Naowarat Cheeptham   +8 more
doaj   +1 more source

Efficacy of soybean-derived crude extract in enzyme-induced carbonate precipitation as soil-improvement technique

International Journal of Geo-Engineering
Calcium carbonate precipitation using a urease enzyme, referred to herein as Enzyme-Induced Carbonate Precipitation (EICP) is a technique for soil improvement. In this technique, a mixed solution composed of reagents and the urease enzyme, which produces
Galih Bhekti Sula Pratama, Hideaki Yasuhara, Naoki Kinoshita, Heriansyah Putra, Abdullah Almajed, Satoru Fukugaichi, Zalfa Maulida Ihsani   +6 more
doaj   +1 more source

Role of VicRKX and GlnR in pH-Dependent Regulation of the Streptococcus salivarius 57.I Urease Operon

mSphere, 2016
Ureolysis by Streptococcus salivarius is critical for pH homeostasis of dental plaque and prevention of dental caries. The expression of S. salivarius urease is induced by acidic pH and carbohydrate excess.
Szu-Chuan Huang, Yi-Ywan M. Chen
doaj   +1 more source

Synthesis, enzyme inhibition and anticancer investigation of unsymmetrical 1,3-disubstituted ureas [PDF]

Journal of the Serbian Chemical Society, 2014
In this research work seventeen urea derivatives, including five new derivatives N-mesityl-N'-(3-methylphenyl)urea (2), N-(3-methoxyphenyl)-N'-(3-methylphenyl)urea (4), N-mesityl-N'-(4-methylphenyl)urea (6), N-(1,3-benzothiazol-2-yl)-N'-(3 ...
Mustafa Sana, Perveen Shahnaz, Khan Ajmal   +2 more
doaj   +1 more source