Results 101 to 110 of about 28,334 (290)

Inborn errors of immunity in children with neuroinflammation

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu   +5 more
wiley   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

A prospective, randomized, double-blind, placebo-controlled, multicenter study of thiamin plus folic acid in the treatment of cognitive impairment in patients undergoing maintenance hemodialysis

open access: yesRenal Failure
This prospective, randomized, double-blind, placebo-controlled trial investigated the efficacy and safety of thiamin and folic acid for cognitive impairment in maintenance hemodialysis (MHD) patients. A total of 215 MHD patients aged 18–75 with cognitive
Kewei Xie   +20 more
doaj   +1 more source

Is uremia an example of acquired inhibition of receptor-mediated endocytosis?

open access: yes, 1993
Many factors that inhibit receptor-mediated endocytosis (RME) at postreceptor level in vitro have been described: (i) high concentration of urea, (ii) lowering of intracellular pH, (iii) hypotonic or hypertonic media, (iv) intracellular potassium ...
Stantchev, Tzanko S.; Medical University of Varna
core   +1 more source

Dialysis and Pregnancy: Optimizing Therapy for Best Maternal and Fetal Outcomes

open access: yesHemodialysis International, EarlyView.
ABSTRACT Pregnancy in women with end‐stage kidney disease (ESKD) requiring dialysis remains high risk, with significant maternal and fetal complications. While fertility rates are markedly reduced in this population, advances in dialysis care and obstetric management have led to increasing reports of successful pregnancies.
Shreepriya Mangalgi, Silvi Shah
wiley   +1 more source

Therapeutic efficacy of lanthanum carbonate combined with meglumine cyclophosphate on patients with uremia cardiomyopathy

open access: yesLinchuang shenzangbing zazhi, 2015
Objective To study the relationship of heart rate turbulence(HRT) in patients with uremia cardiomyopathy and investigate the curative effect and security of lanthanum carbonate combined with meglumine cyclophosphate(MAC) in patients with uremia ...
CHEN Xin   +3 more
doaj  

Sexual dysfunction in the male patient with uremia: A reappraisal

open access: yes, 1981
Sexual dysfunction in the male patient with uremia: A reappraisal. Partial or complete impotence is common in uremia. It is not clear whether the impotence is organic or psychogenic in nature and whether uremia itself or the state of chronic illness is ...
Massry, Shaul G.   +3 more
core   +1 more source

Intima‐Media Thickness Progression Rate and Primary Unassisted Patency Failure in Arteriovenous Fistulas: A Prospective Cohort Study

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background Failure of autogenous arteriovenous fistulas (AV fistulas) due to venous neointimal hyperplasia is a major clinical challenge. Whether the rate of progression in venous intima‐media thickness predicts primary unassisted patency failure remains unknown.
Gen Li, Zhengjiang Cao
wiley   +1 more source

Compositional characteristics of the gut microbiome in patients with uremia

open access: yes
During acute or chronic uremia, the cumulative harmful effects of uremic toxins result in numerous health problems and, ultimately, mortality. Previous research has identified that uremic retention solutes originate from the gut microbiome, indicating ...
Peng Wang   +7 more
core   +1 more source

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