Results 81 to 90 of about 30,710 (255)

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Autonomic dysfunction in uremia

, 2001
Autonomic nervous system dysfunction is a common feature in uremia and may have a number of clinical sequelae. Simple cardiovascular reflex screening can be performed in patients during conservative treatment, on periodic dialysis therapy, or after ...
VITA, Giuseppe, MUSOLINO, Rosa Fortunata, BELLINGHIERI, Guido, SANTORO, Domenico, SAVICA, Vincenzo   +4 more
core   +1 more source

Cardiovascular effects of uremia in apolipoprotein E-deficient mice

, 2009
Udgivelsesdato: 2009-NovThe purpose of this thesis work was to establish an experimental mouse model for studying the pathogenesis and therapy of accelerated atherosclerosis in uremia.
Bro, Susanne
core   +1 more source

Clinical Vignette: Piperacillin/tazobactam‐associated myoclonic status epilepticus in a patient with end‐stage renal failure on hemodialysis

Epileptic Disorders, EarlyView.
O. M. Malanga, G. Giovannelli, G. Pastorelli, S. Fittante, A. Poggesi, E. Rosati   +5 more
wiley   +1 more source

Halting the Progression of Acute Kidney Injury: A Tubular‐Inspired Reusable Detoxifier Against Protein‐Bound Uremic Toxins and Oxidative Stress

SusMat, EarlyView.
This graphical ToC illustrates a tubular‐inspired detoxifier (SDCMs–DS) that halts acute kidney injury progression. Inspired by proximal tubular epithelial cells (PTECs), the biomimetic design combines dissociation‐adsorption clearance of protein‐bound uremic toxins (PBUTs) with antioxidant protection. During hemoperfusion, danshensu (DS) released from
Yilin Wang, Jiahao Liang, Xijing Yang, Xin Song, Yujie Xiao, Xiran Zhou, Hongyu Xiang, Shujing Wang, Shengjun Cheng, Xianda Liu, Yu Chen, Weifeng Zhao, Changsheng Zhao   +12 more
wiley   +1 more source

DDRGK1-mediated ER-phagy attenuates acute kidney injury through ER-stress and apoptosis

Cell Death and Disease
Acute kidney injury (AKI) constitutes a prevalent clinical syndrome characterized by elevated morbidity and mortality rates, emerging as a significant public health issue.
Haijiao Jin, Yuanting Yang, Xuying Zhu, Yin Zhou, Yao Xu, Jialin Li, Chaojun Qi, Xinghua Shao, Jingkui Wu, Shan Wu, Hong Cai, Leyi Gu, Shan Mou, Zhaohui Ni, Shu Li, Qisheng Lin   +15 more
doaj   +1 more source

Chronic Kidney Disease Induced Intestinal Mucosal Barrier Damage Associated with Intestinal Oxidative Stress Injury

Gastroenterology Research and Practice, 2016
Background. To investigate whether intestinal mucosal barrier was damaged or not in chronic kidney disease progression and the status of oxidative stress. Methods. Rats were randomized into two groups: a control group and a uremia group.
Chao Yu, Zhen Wang, Shanjun Tan, Qiang Wang, Chunyu Zhou, Xin Kang, Shuang Zhao, Shuai Liu, Huijun Fu, Zhen Yu, Ai Peng   +10 more
doaj   +1 more source

Prognostic value of contrast‐enhanced ultrasound in dogs with acute renal injury treated with haemodialysis

Veterinary Record, Volume 196, Issue 6, 15/22 March 2025.
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli, Ilaria Lippi, Tina Pelligra, Simonetta Citi   +3 more
wiley   +1 more source

Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease

VIEW, EarlyView.
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin, Lijie Ma, Yuqing Yuan, Kaiyi Zhu, Zhaohui Tong, Qianmei Sun   +5 more
wiley   +1 more source

Ca transport of sarcoplasmic reticulum during experimental uremia

, 1976
In uremia, the membrane composition of the SR is altered: the ATPase carrier complex decreases, the phosphatide, but not the cholesterol content of the membranes decreases and the fatty acid pattern changes.
Heimberg, K., Matthews, C., Ritz, E.
core   +1 more source