Results 71 to 80 of about 30,710 (255)

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

Renal cortical mitochondrial transport of calcium in chronic uremia [PDF]

, 1988
Renal cortical mitochondrial transport of calcium in chronic uremia. Calcium overload of tubular cells may occur in uremia, and may be the underlying functional abnormality in the continued deterioration of renal function in chronic renal failure.
Chaimovitz, Cidio, Shoshan, Varda, Kol, Rina, Shainkin-Kestenbaum, Ruth, Conforty, Aviva, Rapoport, Jayson   +5 more
core   +1 more source

Intraoperative Evaluation of Sarcoma Surgical Margins With Indocyanine Green Fluorescence Imaging: Results From an Observational Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Sarcomas are rare malignancies that affect both adults and children. Surgical removal with negative histopathological margins is the foundation of sarcoma treatment. Failure to achieve negative margins puts patients at risk of local recurrence (LR). LR rates range between 10% and 30%.
Sumail Bhogal, Matthew Gong, William Li, Brenda Diergaarde, Alma Heyl, Clark Roth, Lawrence Garvin II, Alexander Hoffman, Amanda Locker, Ines Lohse, Maria Silvaggio, Stella Lee, Richard McGough, Kurt Weiss   +13 more
wiley   +1 more source

Design and Psychometric Properties of a Self-Care Questionnaire for the Elderly

Sālmand, 2015
Objectives: The purpose of this study was to design an Iranian cultural adaptable questionnaire for the assessment of self-care in the elderly. Methods & Materials: This methodological study was conducted in 2 phases. In the first phase, items&
Masomeh Hemmati Maslak Pak, Leila Hashemlo   +1 more
doaj  

Identification of Immune-Related Genes as Biomarkers for Uremia

International Journal of General Medicine, 2023
Dongning Lyu, Guangyu He, Kan Zhou, Jin Xu, Haifei Zeng, Tongyu Li, Ningbo Tang Department of Nephrology Clinic, Guangxi International Zhuang Medicine Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, Guangxi, People’s Republic of ...
Lyu D, He G, Zhou K, Xu J, Zeng H, Li T, Tang N   +6 more
doaj  

Urea Synthesis by Perfused Rat Liver in Experimental Uremia

, 1980
Urea synthesis was examined in experimental uremia using the isolated perfused rat liver in order to assure strict control of substrate (NH4Cl) presented to the liver. Acute uremia was created in female Sprague-Dawley rats by bilateral nephrectomy (n = 7)
Obaya, Hilda, Schiff, Eugene, Parker, Tally, Perez, Guido, Rietberg, Barbara, Owens, Barbara   +5 more
core   +1 more source

Apoptosis of leukocytes: Basic concepts and implications in uremia [PDF]

, 2001
Apoptosis of leukocytes: Basic concepts and implications in uremia. Circulating blood leukocytes have short life expectancies and end their lives by committing programmed cell death or apoptosis.
Jaber, Bertrand L. [UNIFESP], Pereira, Brian J.G., Cendoroglo Neto, Miguel [UNIFESP], Cendoroglo, Miguel, Balakrishnan, Vaidyanathapuram S., Jaber, Bertrand L., Pereira, Brian JG, King, Andrew J., Perianayagam, Mary C.   +8 more
core   +1 more source

Chronic Kidney Disease‐Associated Pruritus Is Linked to Selective Enrichment of Taurine‐Conjugated Bile Acid Subspecies

JEADV Clinical Practice, EarlyView.
Chronic kidney disease‐associated pruritus (CKDaP) is a frequent complication of advanced CKD with an incompletely understood pathophysiology. We identified a significantly altered glycine‐to‐taurine conjugated bile acid ratio in patients with CKDaP despite unchanged total serum bile acid concentrations.
Miriam M. Düll, Manfred Rauh, Peter Dietrich, Marcel Vetter, Jonas Schmid, Thomas Mettang, Andreas E. Kremer   +6 more
wiley   +1 more source

Bidirectional Mendelian Randomization analysis of iron status and uremia: no evidence of a causal relationship

Renal Failure
Iron status and uremia have been linked, but the causality remains ambiguous. This bidirectional study aimed to explore the causal association between genetically predicted iron status and uremia.
Jianwei Chen, Hu Zhao, Yang He, Chen Lin, Yu Wang   +4 more
doaj   +1 more source

Homocysteine Aggravates Intestinal Epithelial Barrier Dysfunction in Rats with Experimental Uremia

Kidney & Blood Pressure Research, 2018
Background/Aims: Previous studies have shown that homocysteine (Hcy) is an important intestinal-derived uremic toxin. However, whether Hcy is involved in the epithelial barrier dysfunction observed in uremia remains unclear.
Shanshan Liang, Sixiu Liu, Hua Liu, Xin He, Lingshuang Sun, Lei Chen, Meng Wei, Fanfan Gao, Hongli Jiang   +8 more
doaj   +1 more source