Results 71 to 80 of about 23,676 (235)
Renal Impairment Does Not Affect Pharmacokinetics, Safety or Tolerability of Zenagamtide
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Zenagamtide is a novel, unimolecular glucagon‐like peptide‐1 and amylin receptor agonist in development for weight management and Type 2 diabetes. This study investigated the pharmacokinetic (PK) properties, safety and tolerability of zenagamtide in participants with various degrees of renal impairment versus participants with normal ...
Lykke Ida Kaas Oldenburg +6 more
wiley +1 more source
Urology Research and Practice, 2019 The hundredth anniversary of the worst ever civilian maritime disaster was also the fiftieth anniversary of the death of arguably its most controversial character, Captain Stanley Lord, skipper of the Californian, a “tramp” steamer that became entrapped ...
Lawrence Michael Wyner
doaj +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Light chain monoclonal gammopathy of undetermined significance (LC‐MGUS) is defined by an abnormal serum free light chain ratio and elevated involved light chain in the absence of a detectable immunoglobulin heavy chain on immunofixation and of end‐organ damage attributable to a plasma cell disorder.
Sigurður Yngvi Kristinsson +2 more
wiley +1 more source
Hemodialysis International, EarlyView.ABSTRACT Background Failure of autogenous arteriovenous fistulas (AV fistulas) due to venous neointimal hyperplasia is a major clinical challenge. Whether the rate of progression in venous intima‐media thickness predicts primary unassisted patency failure remains unknown.
Gen Li, Zhengjiang Cao
wiley +1 more source
Renal FailureThis prospective, randomized, double-blind, placebo-controlled trial investigated the efficacy and safety of thiamin and folic acid for cognitive impairment in maintenance hemodialysis (MHD) patients. A total of 215 MHD patients aged 18–75 with cognitive
Kewei Xie +20 more
doaj +1 more source
Small Bowel Lesions and Bleeding Risk in Hemodialysis Patients: A Narrative Review
Hemodialysis International, EarlyView.ABSTRACT Background Gastrointestinal bleeding is very common among hemodialysis patients. This high bleeding risk is caused by uremic platelet dysfunction, vascular fragility, intradialytic hemodynamic instability, and widespread antithrombotic therapy.
Andreas Smyrlis +3 more
wiley +1 more source
Hemodialysis International, EarlyView.ABSTRACT Introduction Tenapanor, a minimally absorbed intestinal NHE3 inhibitor approved for hyperphosphatemia in dialysis, lowers phosphate and reduces intestinal sodium absorption. Its sodium–water signal may have implications beyond phosphate but remains poorly separated from diarrhea‐mediated losses and dialysis prescription artifacts. Methods This
Lucas Maciel de Almeida Corrêa +8 more
wiley +1 more source
Hemodialysis International, EarlyView.ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra +2 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2015 Objective To study the relationship of heart rate turbulence(HRT) in patients with uremia cardiomyopathy and investigate the curative effect and security of lanthanum carbonate combined with meglumine cyclophosphate(MAC) in patients with uremia ...
CHEN Xin +3 more
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